Kidney and Pancreas Transplantation

A Practical Guide

Author: T. R. Srinivas

Publisher: Springer Science & Business Media

ISBN:

Category: Medical

Page: 441

View: 522

The transplant physicians and surgeons at Cleveland Clinic have collaborated to produce, Kidney and Pancreas Transplantation: A Practical Guide. This volume is devoted to kidney and pancreas transplantation and is well grounded in scientific principles, quantitative clinical reasoning, clinical pharmacology, tested clinical practices and overall clinical applicability. Also addressed are key aspects in the initiation, maintenance and sustained growth of viable clinical programs in kidney and pancreas transplantation. Kidney and Pancreas Transplantation: A Practical Guide will be of great value to transplant physicians as well as medical and surgical fellows who intend to pursue an interest in transplantation.

Pancreas Transplantation

Author: Luis H. Toledo-Pereyra

Publisher: Springer Science & Business Media

ISBN:

Category: Medical

Page: 298

View: 563

In December, 1966, two patients dying of months after the transplants had been per uremia as a result of diabetic kidney disease formed. This was long enough, however, to were offered a small chance of survival. Ac establish unequivocally in both patients cording to the thinking of the time, it was that an endocrine organ, the pancreas, could inappropriate-and perhaps even unethical function normally and for many days as a to offer them either chronic hemodialysis or human-to-human graft. The patients had kidney transplantation. These were considered become normoglycemic independent of insulin a waste of effort because it was believed that injections. scarce medical resources should not be spent The possible long-term benefits of restoring on patients, uremic or not, whose chances of insulin function were hotly argued then, and surviving for more than a few months were they have not been fully determined 20 years thought to be very small. Reduced to its later. It seems to me now, however, that the essence, the idea was that diabetic patients basic premise is sounder than I realized in were terrible risks and would remain so even if 1966: if one could restore an effective, norm the uremia were corrected.

Kidney and Pancreas Transplantation: Operative Techniques and Medical Management

Author: Ernesto P. Molmenti

Publisher: McGraw-Hill Education / Medical

ISBN:

Category: Medical

Page: 512

View: 656

With 600 photos and illustrations—this highly visual, concise guide provides everything you need to know about transplanting the kidney and pancreas The kidney is are the most commonly transplanted organ, and the liver is the second most-common (80% of pancreas transplantations are done in combination with kidneys). Kidney and Pancreas Transplantation provides a concise, visual approach to learning through hundreds of high-quality operative images and bulleted text—everything you need to successfully perform operations on and medically manage these vital organs. It covers every relevant topic, including ethics, complications, live and deceased donor evaluation, pharmacology, and anesthesia. Each chapter provides an overview of the essentials of kidney disease, pre- and post-operative patient management, operative techniques, pathology, and imaging.

Kidney and Pancreas Transplantation, Second Edition

Author: Ingemar J.A. Davidson

Publisher: CRC Press

ISBN:

Category: Medical

Page: 228

View: 307

This book addresses peritransplant surgical management aspects in general, with emphasis on detailed intraoperative surgical technique. This is displayed in the detailed graphic representation which is the result of many hours of communication from the surgeon's view to the illustrator's hand. When writing this book, the authors have mainly had the young training surgeon in mind; however, this handbook will prove a valuable resource for many, including operating room personnel, transplant coordinators and transplant nephrologists.

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas

Volume 1

Author: Giuseppe Orlando

Publisher: Academic Press

ISBN:

Category: Science

Page: 890

View: 350

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 1, sets a new standard in transplant and regenerative medicine. The book details the-state-of-the-art in modern whole pancreas and islet transplantation, including donor selection, immunosuppression, complications, allograft pathology, and more. As regenerative medicine is changing the premise of solid organ transplantation, this volume catalogs the technologies being developed and the methods being implemented to bioengineer or regenerate the endocrine pancreas in order to more effectively treat diabetes. Edited and authored by unparalleled leaders in the field, this new volume argues for a much needed synergy between organ transplantation and regenerative medicine. Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation Includes sections that address donor selection, immunosuppression, complications, allograft pathology, and more Offers an update on the progress of regenerative medicine research aimed at beta cells replacement in the treatment of diabetes

Kidney & Pancreas Transplantation

Author: Ernesto Pompeo Molmenti

Publisher: Jaypee Brothers,Medical Publishers Pvt. Limited

ISBN:

Category: Medical

Page: 614

View: 944

Kidney & Pancreas Transplantation is a comprehensive collection of considerations for organ transplantation, starting from candidate evaluation to surgical techniques and complications, and cutting-edge material on robotic surgical techniques. Divided into 22 sections, comprising 72 chapters, the book clearly illustrates the step-by-step surgical procedures of kidney and pancreas transplantation surgeries. Topics include islet cell transplantation, epigenetics, imaging complications, pathology, dermatologic manifestations, obesity and metabolic syndromes. The section ‘Operative Techniques: Donor’ offers extensive coverage of live donor nephrectomy, methods for avoiding and managing hazards during live donor nephrectomies and deceased donor procurement. Kidney & Pancreas Transplantation has a multidisciplinary approach, comprised of contributions from internationally renowned nephrologists. It offers practical guidance and information relevant to a diverse audience of physicians. Key Points Contributions from multidisciplinary experts Edited by Professor Molmenti at the LIJ School of Medicine, New York 1230 (800 full colour) images, illustrations and tables

Kidney Transplantation, Bioengineering, and Regeneration

Kidney Transplantation in the Regenerative Medicine Era

Author: Giuseppe Orlando

Publisher: Academic Press

ISBN:

Category: Science

Page: 1252

View: 924

Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney. Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function

Current Issues and Future Direction in Kidney Transplantation

Author: Thomas Rath

Publisher: IntechOpen

ISBN:

Category: Medical

Page: 492

View: 404

The here presented book covers different areas of clinical and scientific interest, reaching from donor evaluation to newest methods in immunological diagnostics. But also aspects of daily care of transplant recipients can be found in the carefully selected chapters. Everything driven by the aim to improve the care for all of our transplanted patients.

Kidney and Pancreas Transplantation

Author: Ingemar Davidson

Publisher:

ISBN:

Category: Kidneys

Page: 244

View: 969

This book addresses peritransplant surgical management aspects in general, with emphasis on detailed intraoperative surgical technique. This is displayed in the detailed graphic representation which is the result of many hours of communication from the surgeon's view to the illustrator's hand. When writing this book, the authors have mainly had the young training surgeon in mind; however, this handbook will prove a valuable resource for many, including operating room personnel, transplant coordinators and transplant nephrologists.

Kidney Transplant

A Fairy Tale in Real Life: Kidney Pancreas Transplant Stories

Author: Fernando Benz

Publisher:

ISBN:

Category:

Page: 84

View: 201

Kidney transplantation or renal transplantation is the organ transplant of a kidney into a patient with end-stage kidney disease. Kidney transplantation is typically classified as deceased-donor or living-donor transplantation depending on the source of the donor organ. This book contains three amazing stories of miracles made possible through the love of God, and His blessings on the lives of the people involved...

Transplantation of the Pancreas

Author: Rainer W.G. Gruessner

Publisher: Springer Science & Business Media

ISBN:

Category: Medical

Page: 676

View: 901

Although pancreas transplants have been performed for more than 30 years, the last few years have witnessed significant growth in the options available for pancreas transplantation as well as subtantial improvements in outcome. It is therefore appropriate that a new text summarize the recent advances and put forth the standard of future care. Transplantation of the Pancreas, edited by Drs. Gruessner and Sutherland fulfills this mission by providing a state-of-the-art, definitive reference work on pancreas transplantation for transplant surgeons and physicians as well as for endocrinologists, diabetologists, nephrologists, and neurologist. The editors, from the renowned University of Minnesota Transplant Division and the Diabetes Institute, have assembled a group of renowned experts to provide an all inclusive overview of pancreas transplantation. The text features insights on the pathophysiology of diabetes mellitus and the limitations of nontransplant treatments, highlights experimental research and clinical history of pancreas transplantation, and compares and contrasts different surgical procedures. The discussions detail the broad spectrum of posttransplant complications and their treatments, which frequently require skills in general, vascular, and laparoscopic surgery, interventional radiology, critical care, and infectious disease. Chapters on immunosuppression, immunology, pathology, long-term outcome, quality of life, and cost-effectiveness focus on issues unique to pancreas recipients. Evolving areas, such as pretransplant evaluation of pancreas transplant candidates, living donation, and the current status of islet transplantation are discussed. Augmented by more than 280 illustrations, including full color line drawings created exclusively for the text, this book is the standard reference for all transplant professionals as well as all physicians caring for diabetic patients.

P072 RESULTS OF SIMULTANEOUS PANCREAS AND KIDNEY TRANSPLANTATION AFTER NEARLY 10 YEARS OF EXPERIENCE IN OUR HOSPITAL.

Author:

Publisher:

ISBN:

Category:

Page:

View: 563

Introduction: Simultaneous Pancreas and Kidney (SPK) transplantation is the most suitable option for patients with Diabetes Mellitus (DM) and Chronic Renal Failure (CRF) and improves quality of life of these patients.Objective and Methods: evaluate the results of our SPK transplantation in our hospital. From 27/02/2009 to 20/11/2018 70 patients received a pancreas transplantation, 68 SPK and 2 patients received a second pancreas after kidney (PAK) because of a failure of the pancreas graft surgery, (these two were excluded from the study). Retrospective study where we analyzed demographic characteristics, evolution and survival of the grafts and patients. Kidney graft failure was need of restarting dialysis, and pancreas failure, need of insulin administration. Student t, X2 and Mann Whitney tests were done.Results: in this period 68 SPK were carried out in the University Hospital of Salamanca, Spain. Recipients average age was 40.6 +/- 7.75. 50 men (73.52%) and 18 women (26.47%). 7 patients received a pre-emptive SPK (10.29%). 19 (27.94%) were in Peritoneal dialysis (PD) and 42 (61,76%) were receiving Hemodialysis (HD). Pancreas cold ischemia time (CIT) average 11 hours 20 minutes and renal CIT average14 hours 10 minutes. 3 patients died so patient survival was 95.58%. 7 kidneys were lost but 4 of those patients had already received a second kidney transplantation. Renal survival was 85%, dead censored was 93%. Pancreas survival was 92% but dead censored was 97 %. Renal function and glycosylate hemoglobin are shown in the table 1. Of the values studied we didnu2019t find any association between them and either renal of pancreas graft failure. ConclusionsAfter nearly 10 years we can say that the SPK transplantation is the most suitable treatment for patients with DM and CRF. We didnu2019t find any statistical association between the reviewed values and the prognosis of this transplantation.Creatinine 1 year post-transplantation (post-tr)t1,15u00b10,31 mg/dlHbA1C 1 year post-trt5,33u00b10,48 %Creatinine 5 years post-trt1,22u00b10,29 mg/dl HbA1C 5 years post-trt5,41u00b1037 %Creatinine November 2018t1,19u00b1 0,28 mg/dlHbA1C November 2018t5,32u00b1 0,37 %.

Results of Simultaneous Pancreas and Kidney Transplantation After Nearly 10 Years of Experience in Our Hospital

Author:

Publisher:

ISBN:

Category:

Page:

View: 913

Introduction: Simultaneous Pancreas and Kidney (SPK) transplantation is the most suitable option for patients with Diabetes Mellitus (DM) and Chronic Renal Failure (CRF) and improves quality of life of these patients.Objective and Methods: evaluate the results of our SPK transplantation in our hospital. From 27/02/2009 to 20/11/2018 70 patients received a pancreas transplantation, 68 SPK and 2 patients received a second pancreas after kidney (PAK) because of a failure of the pancreas graft surgery, (these two were excluded from the study). Retrospective study where we analyzed demographic characteristics, evolution and survival of the grafts and patients. Kidney graft failure was need of restarting dialysis, and pancreas failure, need of insulin administration. Student t, X2 and Mann Whitney tests were done.Results: in this period 68 SPK were carried out in the University Hospital of Salamanca, Spain. Recipients average age was 40.6 +/- 7.75. 50 men (73.52%) and 18 women (26.47%). 7 patients received a pre-emptive SPK (10.29%). 19 (27.94%) were in Peritoneal dialysis (PD) and 42 (61,76%) were receiving Hemodialysis (HD). Pancreas cold ischemia time (CIT) average 11 hours 20 minutes and renal CIT average14 hours 10 minutes. 3 patients died so patient survival was 95.58%. 7 kidneys were lost but 4 of those patients had already received a second kidney transplantation. Renal survival was 85%, dead censored was 93%. Pancreas survival was 92% but dead censored was 97 %. Renal function and glycosylate hemoglobin are shown in the table 1. Of the values studied we didnu2019t find any association between them and either renal of pancreas graft failure. ConclusionsAfter nearly 10 years we can say that the SPK transplantation is the most suitable treatment for patients with DM and CRF. We didnu2019t find any statistical association between the reviewed values and the prognosis of this transplantation.Creatinine 1 year post-transplantation (post-tr)t1,15u00b10,31 mg/dlHbA1C 1 year post-trt5,33u00b10,48 %Creatinine 5 years post-trt1,22u00b10,29 mg/dl HbA1C 5 years post-trt5,41u00b1037 %Creatinine November 2018t1,19u00b1 0,28 mg/dlHbA1C November 2018t5,32u00b1 0,37 %.

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas

Volume 2

Author: Giuseppe Orlando

Publisher: Academic Press

ISBN:

Category: Science

Page: 560

View: 242

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 2, sets a new standard in transplant and regenerative medicine. The book details the state-of-the-art in modern islet auto-transplantation, also discussing current progress in regenerative medicine research in diabetes medicine. Regenerative medicine is changing the premise of solid organ transplantation, hence this volume catalogs technologies being developed and methods being implemented. Bioengineering and regenerating beta cells, clinical pancreas and islet transplantation, tissue engineering, biomaterial sciences, stem cell biology and developmental biology are all addressed and applied directly to diabetes medicine. Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation Addresses imaging, treatment, scaffold technology, the use of stem cells to generate insulin, 3D printing, and more Offers an update on the progress of regenerative medicine research aimed at beta cell replacement for the treatment of diabetes

Pancreas Transplantation

Author: Pedro Ventura-Aguiar

Publisher:

ISBN:

Category: Medicine

Page:

View: 465

Pancreas transplantation is a treatment alternative to patients with type 1 diabetes, particularly to those with associated end-stage renal disease (ESRD). Recently, pancreas transplant centers have widened their criteria for pancreas transplantation to selected type 2 diabetic patients. This chapter reviews the most important topics on pancreas transplantation, including epidemiology and natural history of type I and type II diabetes, indications for pancreas transplantation, different alternatives for pancreas transplant recipients (simultaneous kidney-pancreas transplantation, pancreas after kidney, or pancreas transplant alone-PTA), and their outcomes. This chapter gives a detailed description of the surgical procedure for pancreas procurement and engraftment, as well as the most frequent surgical complications. An approach to the management of the recipient following pancreas transplantation (immunosuppression and infection prophylaxis) is also discussed. Finally, outcomes and complications following the pancreas transplantation are reviewed.