Who is his next victim? Terrifyingly suspenseful, inventive and emotionally intricate, Intensity is a gripping novel from bestselling author Dean Koontz. Perfect for fans of Stephen King and Richard Laymon. 'Tumbling, hallucinogenic prose... The story does not move so much as rocket up the... gloomy highway with the reader in violent pursuit' - The New York Times Edgler Vess is a sociopath intent on murder. He lives for one purpose only: to satisfy all appetites as they arise, seeking ever more outrageous experience. To live with intensity. When he attacks her friend, Laura, Chyna Shepherd is saved by the instincts developed during a dark and turbulent childhood. Not knowing Laura is already dead, Chyna follows, hoping to save her friend, as Vess carries her body to his motor home - a dungeon and morgue on wheels. The killer, unaware of her presence, drives away. But Chyna is now trapped in his dangerous orbit. Her sole aim is to get out alive, but when she learns the identity of the killer's next intended victim, she knows she must act to save that precious life - and take risks beyond any that she ever imagined she could endure. What readers are saying about Intensity: 'Intoxicating, and superbly written' '[Dean Koontz] writes with style and imagination, and he maintains an electrifying, emotional pace throughout the book: this is page-turning fiction at its dynamic best' 'Absolutely, utterly brilliant'
Issues in Orthopedics and Occupational and Sports Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Orthopedics and Occupational and Sports Medicine. The editors have built Issues in Orthopedics and Occupational and Sports Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Orthopedics and Occupational and Sports Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Orthopedics and Occupational and Sports Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
This issue of Interventional Cardiology Clinics, edited by Allen Jeremias, is devoted to Intravascular Physiology. Dr. Jeremias assembled a group of expert contributors to review the following topics: Evolution of Coronary Physiology – Basic Concepts of FFR and CFR; Concept of "Functional PCI" – The Rational for Physiologic Lesion Assessment for PCI Guidance; Limitations and Pitfalls of FFR and Adenosine-Induced Hyperemia; Evidence for the Use of FFR to Guide Clinical Decision-Making – The Landmark FFR Clinical Trials; Evaluation of Microvascular Disease and Clinical Outcomes; Hyperemic vs. Resting Indices for the Assessment of CAD; FFR for the Evaluation of Tandem and Bifurcations Lesions, Left Main, and Acute Coronary Syndromes; and CT-FFR: Basic Concept and Clinical Implementation.
Whether you are in the lab or the office, stay current in the ever-evolving field of electrophysiology with Catheter Ablation of Cardiac Arrhythmias. Organized by type of arrhythmia, this simple yet comprehensive medical reference book provides detailed information on anatomy, diagnoses, mapping/ablation, and troubleshooting. The book also extensively covers the updated, basic concepts of transcatheter energy applications and currently available mapping/imaging tools for ablation. Improve accuracy with assistance from advanced catheter mapping and navigation systems, and the use of intracardiac echocardiography to assist accurate diagnosis and ablation. Stay current on timely topics like contemporary cardiac mapping and imaging techniques, atrial tachycardia and flutter, atrial fibrillation, atrioventricular nodal reentrant tachycardia, tachycardias related to accessory atrioventricular connections, and ventricular tachycardia, transseptal catheterization, ablation for pediatric patients, and patient safety and complications. Get the most comprehensive and detailed coverage of arrhythmias and ablation technologies, highlighted by a systematic approach to troubleshooting specific problems encountered in the laboratory - complete with solutions. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly chapter format. Master each approach with exceptional visual guidance from tables, illustrations, and high-quality figures. Stay up to date with enhanced and expanded chapters, as well as several hundred new figures, web-based videos, and updated references. Explore recent developments in the areas of atrial fibrillation and ventricular tachycardias. Learn from experts in the field with nearly half of the chapters composed by new authors. Improve content knowledge in relation to anatomy with new chapters focusing on hemodynamic support during VT ablation, rotor mapping in atrial fibrillation, and hybrid procedures. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.
This work represents an inventive attempt to apply recent advances in nanotechnology to identify and characterise novel polymer systems for drug delivery through the skin. Atomic force microscopy (AFM) measurements of the nanoscale mechanical properties of topical, drug-containing polymeric films enabled the author to identify optimal compositions, in terms of flexibility and substantivity, for application to the skin. To elucidate the enhanced drug release from polyacrylate films incorporating medium chain triglycerides, the author combined AFM studies with the complementary technique of Raman micro-spectroscopy. This experimental strategy revealed that the significant increase in the drug released from these films is the result of a nanoscale two-phase structure. Finally, in experiments examining the microporation of skin using femtosecond laser ablation, the author demonstrated that the threshold at which the skin's barrier function is undermined can be dramatically reduced by the pre-application of ink. The approach allows thermal damage at the pore edge to be minimised, suggesting a very real potential for substantially increasing drug delivery in a minimally invasive fashion.
Now available in a single volume paperback, this advanced reference resource for the novel and novel theory offers authoritative accounts of the history, terminology, and genre of the novel, in over 140 articles of 500-7,000 words. Entries explore the history and tradition of the novel in different areas of the world; formal elements of the novel (story, plot, character, narrator); technical aspects of the genre (such as realism, narrative structure and style); subgenres, including the bildungsroman and the graphic novel; theoretical problems, such as definitions of the novel; book history; and the novel's relationship to other arts and disciplines. The Encyclopedia is arranged in A-Z format and features entries from an international cast of over 140 scholars, overseen by an advisory board of 37 leading specialists in the field, making this the most authoritative reference resource available on the novel. This essential reference, now available in an easy-to-use, fully indexed single volume paperback, will be a vital addition to the libraries of literature students and scholars everywhere.
To say that the entirety of human experience can be a novelist’s theme is to voice an absurdity. But, as Peter Swiggart convincingly argues, Faulkner’s work can be viewed as an extraordinary attempt to transform the panorama of man’s social experience into thematic material. Faulkner’s two-dimensional characters, his rhetorical circumlocutions, and his technical experiments are efforts to achieve a dramatic focus upon material too unwieldy, at least in principle, for any kind of fictional condensation. Faulkner makes use of devices of stylization that apply to virtually every aspect of his successful novels. For example, the complex facts of Southern history and culture are reduced to the scale of a simplified and yet grandiose social mythology: the degeneration of the white aristocracy, the rise of Snopesism, and the white Southerner’s gradual recognition of his latent sense of racial guilt. Within Faulkner’s fictional universe, human psychology takes the form of absolute distinctions between puritan and nonpuritan characters, between individuals corrupted by moral rationality and those who are simultaneously free of moral corruption and social involvement. In this way Faulkner is able to create the impression of a comprehensive treatment of important social concerns and universal moral issues. Like Henry James, he makes as much as he can of clearly defined dramatic events, until they seem to echo the potential complexity and depth of situations outside the realm of fiction. When this technique is successful the reader is left with the impression that he knows a Faulkner character far better than he could know an actual person. At the same time, the character retains the atmosphere of complexity and mystery imposed upon it by Faulkner’s handling of style and structure. This method of characterization reflects Faulkner’s simplifications of experience and yet suggests the inadequacy of any rigid interpretation of actual behavior. The reader is supplied with special eyeglasses through which the tragedy of the South, as well as humanity’s general inhumanity to itself, can be viewed in a perspective of simultaneous mystery and symbolic clarity.
Mississippi teenager Noel Weatherspoon--a clairvoyant, asthma sufferer, insomniac, dopehead, would-be erotic photographer or baseball star, vandal, and somnambulant mercy killer--finds his life spinning out of control as he struggles to cope with his romantic failures, dark secrets, religious zealots, and more. A first novel. Reprint.
Pringle presents his selections in chronological order and includes a synopsis of the story, a discussion of the author's overall contribution to fantasy literature, critical commentary on the title's significance, and a brief publishing history. An introductory essay tackles the difficulty of defining fantasy, while a "Brief Bibliography" directs readers to other discussions of the genre. By no means a definitive subject guide, this entertaining volume should serve as a solid introduction to the elusive field of imaginative literature.