The major emphasis in this book is a compilation and definition of what is known about components of human milk, including glycoconjugates, that inhibit common pathogens of the infant. Also discussed are other bioactive constituents whose relevant biological roles are also beginning to be defined. Hormonal and cytokine activity, immunomodulating and autoinflammatory agents, xenobiotics, and conditionally essential nutrients in milk could have roles in the protection of the infant, but may also participate in digestive processes, maternal-infant communication, maturation of the gut, central nervous system, and other components of infant growth and development. Like the protective activities, these are discussed in terms of their presence in milk, structures, potential functions, and structure/function relationship. Components whose role is nutritional support during early development of the infant are also included.
Dairy foods have huge potential concerning functional foods. Therefore, there is a tremendous amount of interest in value-added milk products and the identification of components in food which have health benefits. This book provides an overview of these derived components and their diverse activities including: the stimulation of beneficial microflora, alerting the immune system to the presence of potential pathogens and allergens, binding and eliminating toxins, etc.
Human Milk Biochemistry and Infant Formula Manufacturing Technology, Second Edition covers the history of bottle feeding, its advantages and disadvantages when compared with breast-feeding, human milk biochemistry, trends and new developments in infant formula formulation and manufacturing, and best practices in infant formula processing technology and quality control. The book also covers human milk proteomics as a new, separate chapter and provides additional information on infant formula clinical trial guidelines. In addition, the book includes information about the formulation and processing of premature and low birth weight infant formula. This book is sure to be a welcome resource for professionals in the food and infant formula industry, academics and graduate students in fields like nutrition, food sciences, or nursing, nutritionists and health professionals, government officials working in relevant departments, and finally, anyone interested in human milk and infant formula. Reviews both human milk biochemistry and infant formula processing technology for broad coverage Features a comprehensive review on the human milk protein profile using proteomics technology Contains information on infant formula processing technology Provides guidelines on infant formula clinical trials and related topics
Although bioactive compounds in milk and dairy products have beenextensively studied during the last few decades – especiallyin human and bovine milks and some dairy products – very fewpublications on this topic are available, especially in other dairyspecies’ milk and their processed dairy products. Also,little is available in the areas of bioactive and nutraceuticalcompounds in bovine and human milks, while books on other mammalianspecies are non-existent. Bioactive Components in Milk and Dairy Productsextensively covers the bioactive components in milk and dairyproducts of many dairy species, including cows, goats, buffalo,sheep, horse, camel, and other minor species. Park has assembled agroup of internationally reputed scientists in the forefront offunctional milk and dairy products, food science and technology ascontributors to this unique book. Coverage for each of the various dairy species includes:bioactive proteins and peptides; bioactive lipid components;oligosaccharides; growth factors; and other minor bioactivecompounds, such as minerals, vitamins, hormones and nucleotides,etc. Bioactive components are discussed for manufactured dairyproducts, such as caseins, caseinates, and cheeses; yogurtproducts; koumiss and kefir; and whey products. Aimed at food scientists, food technologists, dairymanufacturers, nutritionists, nutraceutical and functional foodsspecialists, allergy specialists, biotechnologists, medical andhealth professionals, and upper level students and faculty in dairyand food sciences and nutrition, Bioactive Components in Milkand Dairy Products is an important resourcefor those who are seeking nutritional, health, and therapeuticvalues or product technology information on milk and dairy productsfrom the dairy cow and speciesbeyond. Areas featured are: Unique coverage of bioactive compounds in milks of the dairycow and minor species, including goat, sheep, buffalo, camel, andmare Identifies bioactive components and their analytical isolationmethods in manufactured dairy products, such as caseins,caseinates, and cheeses; yogurt products; koumiss and kefir; andwhey products Essential for professionals as well as biotechnologyresearchers specializing in functional foods, nutraceuticals,probiotics, and prebiotics Contributed chapters from a team of world-renowned expertscientists
Human milk is uniquely tailored to meet infants’ specific nutritional requirements. However, it is more than just “milk”. This dynamic and bioactive fluid allows mother–infant signalling over lactation, guiding the infant in the developmental and physiological processes. It exerts protection and life-long biological effects, playing a crucial role in promoting healthy growth and optimal cognitive development. The latest scientific advances have provided insight into different components of human milk and their dynamic changes over time. However, the complexity of human milk composition and the synergistic mechanisms responsible for its beneficial health effects have not yet been unravelled. Filling this knowledge gap will shed light on the biology of the developing infant and will contribute to the optimization of infant feeding, particularly that of the most vulnerable infants. Greater understanding of human milk will also help in elucidating the best strategies for its storage and handling. The increasing knowledge on human milk’s bioactive compounds together with the rapidly-advancing technological achievements will greatly enhance their use as prophylactic or therapeutic agents. The current Special Issue aims to welcome original works and literature reviews further exploring the complexity of human milk composition, the mechanisms underlying the beneficial effects associated with breastfeeding, and the factors and determinants involved in lactation, including its promotion and support.
The International Workshop on human lactation dedicated specifically to the topic of Maternal and Environmental Effects on Lactation repre sents the recent progress of research in human lactation. Only four years ago it was clear that we do not yet have sensitive research techniques specifically adapted to the study of human milk. This need was addressed by an NIH convened workshop in 1982, the concensus being that appropriate methods have to be developed for the study of the composition of human milk. The progress in the development of these techniques was the subject of the second workshop on human lactation, dedicated specifically to "Milk Components and Methodologies. " The workshop was held in Colorado in 1984 and resulted in the publication of the first volume in the series of "Human Lactation. " At the Colorado meeting it was readily apparent that considerable progress has been made in the development of sensitive techniques able to quantitate the bioactive components of human milk (enzymes, growth factors, immuno-protective agents) as well as the macro, micro and trace elements. At the Colorado workshop it became clear that these workshops greatly benefit the research of human lactation by enhancing communication and collaboration among the investigators in the field. As a result it was decided to have a future workshop about a year later on the topic of "Maternal-Environmental Effects on Human Lacta tion", and I was charged with chairing it.
Human milk is a complex fluid that provides nutrition and various bioactive components to the developing infant. In human breast milk, human milk oligosaccharides (HMO) are an abundant component. Bifidobacterium are among a select group of bacteria that can consume HMO. In breast-fed infants, Bifidobacterium species are often enriched. The presence of bifidobacteria in the gastrointestinal tract of the developing infant is associated with numerous health benefits. Previous work has shown that strains of Bifidobacterium longum subsp. infantis (B. infantis) and Bifidobacterium bifidum can grow well on HMO as a sole carbon source. Until recently, HMO utilization by Bifidobacterium breve and Bifidobacterium longum subsp. longum (B. longum) has been explored to a lesser extent. Strains B. breve SC95 and B. longum SC596 grow vigorously on pooled HMO and individual HMO sugars as a sole carbon source, and here we examined molecular mechanisms employed for HMO utilization by these unique strains. Transcriptomics analysis identified gene clusters induced during growth on pooled or individual HMO. Characterization of various glycosyl hydrolases with activity on HMO linkages and transporters from B. breve SC95 and B. longum SC596 identified mechanisms of HMO transport and utilization. B. breve SC95 has an intracellular [alpha]-L-fucosidase that is highly induced during growth on 2’-FL. This fucosidase has specificity for 2’-FL over other fucosylated HMO structures. Additionally, here we characterized a novel fucosylated gene cluster from the strain B. longum SC596. This cluster encodes two fucosidases and an ABC transporter specific for fucosylated HMO. This work ultimately provides insights into mechanistic elucidations of “HMO responding” B. breve and B. longum strains.
Protecting Infants through Human Milk: Advancing the Scientific Evidence provides a forum in which basic scientists, clinicians, epidemiologists, and policy makers exchange the latest findings regarding the effects of human milk and breastfeeding on infant and maternal health, thereby fostering new and promising collaborations. This volume also integrates data from animal and in vitro laboratory studies with clinical and population studies to examine human milk production and composition, the mechanisms of infant protection and/or risk from human milk feeding, and proposed interventions related to infant feeding practices. Additionally, it stimulates critical evaluation of, and advances in, the scientific evidence base and research methods, and identifies the research priorities in various areas.
This issue is expected to be in high demand, being extremely valuable to both neonatologists and maternal-fetal medicine physicians. The Guest Editors have put together a very comprehensive issue that looks at the premature infant. Topics include: Moderate Preterm. Late Preterm and Early Term Births: Epidemiology and Trends; Stillbirth Reduction Efforts and Impact on Early Births; Management of Indicated Early Term and Late Preterm Births; Physiological Underpinnings for Clinical Problems in Moderately Preterm, Late Preterm;Brain Maturation in the Second of Half of Pregnancy; Respiratory Disorders in Moderately Preterm, Late Preterm and Early Term Infants; Metabolic and Neurologic Issues in Moderately Preterm, Late Preterm and Early Term Infants; and Quality Initiatives Related to Moderately Preterm, Late Preterm and Early Term Births.
The role of diet in the prevention, control and treatment of diabetes continues to provide significant opportunity for non-pharmaceutical interventions for many of the over 20 million people who live with this disease. Looking beyond traditional dietary controls may lead to more effective, cost efficient, and flexible options for many patients. Bioactive Food as Dietary Interventions for Diabetes is the only available scientific resource focused on exploring the latest advances in bioactive food research, and the potential benefit of bioactive food choice on the diabetic condition. Written by experts from around the world, it presents important information that can help improve the health of those at risk for diabetes and diabetes related conditions using food selection as its foundation. Focuses on the role of bioactive foods in addressing pre-diabetes symptoms, their potential to complement other treatments for those suffering from diabetes and diabetic-related obesity and other health issues Documents foods that can affect metabolic syndrome and ways the associated information could be used to understand other diseases that share common etiological pathways Includes insights from experts from around the world, providing global perspectives and options based on various regional foods
Nutrition is an important aspect of care for any patient entering the hospital, but the patient admitted to the intensive care unit (ICU) is at an even higher risk for nutritional compromise. Nutrition affects all ages, from the neonate to the geriatric patient, and all patient populations. Evidence-based practice guidelines regarding appropriate nutritional support within the critical care setting are published. Yet, researchers continue to identify that despite published evidence, countless ICU patients continue to lack adequate and timely nutritional support on admission. Each of the authors in this issue promotes nutrition in their careers and individual practice areas, which brings knowledge from many different arenas throughout the nation. This issue discusses nutrition throughout the lifespan, special patient populations, implementation of guidelines, and how nutrition is being utilized as medical therapy.
Infectious Diseases of the Fetus and Newborn Infant, written and edited by Drs. Remington, Klein, Wilson, Nizet, and Maldonado, remains the definitive source of information in this field. The 7th edition of this authoritative reference provides the most up-to-date and complete guidance on infections found in utero, during delivery, and in the neonatal period in both premature and term infants. Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the latest findings about new antimicrobial agents, gram-negative infections and their management, and recommendations for immunization of the fetus/mother. Nationally and internationally recognized in immunology and infectious diseases, new associate editors Nizet and Maldonado bring new insight and fresh perspective to the book. Get the latest information on maternal infections when they are pertinent to the infant or developing fetus, including disease transmission through breastfeeding Diagnose, prevent, and treat neonatal infectious diseases with expert guidance from the world's leading authorities and evidence-based recommendations. Incorporate the latest findings about infections found in utero, during delivery, and in the neonatal period. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format Get fresh perspectives from two new associate editors—Drs. Yvonne Maldonado, head of the Pediatric Infectious Disease program at Stanford, and Victor Nizet, Professor of Pediatrics & Pharmacy at University of California, San Diego and UCSD School of Medicine. Keep up with the most relevant topics in fetal/neonatal infectious disease including new antimicrobial agents, gram- negative infections and their management, and recommendations for immunization of the fetus/mother. Overcome the clinical challenges in developing countries where access to proper medical care is limited. Apply the latest recommendations for H1N1 virus and vaccines. Identify and treat infections with the latest evidence-based information on fighting life-threatening diseases in the fetus and newborn infants.
Avery’s Diseases of the Newborn, edited by Christine A. Gleason and Sherin U. Devaskar, is a practical, clinical reference for diagnosing and managing of all the important diseases affecting newborns. Thoroughly revised by a team of new editors, this edition provides new perspectives and updated coverage of genetics, nutrition, respiratory conditions, MRSA, neonatal pain, cardiovascular fetal interventions, care of the late preterm infant, and more. This authoritative reference is ideal as a clinical resource or subspecialty review tool. Treat newborns effectively with focused coverage of diagnosis and management, including pertinent developmental physiology and the pathogenesis of neonatal problems. Meet every challenge you face in neonatology with Avery’s authoritative, comprehensive clinical resource and subspecialty review tool. Navigate quickly and easily with extensive cross-referencing throughout the organ-related sections. Stay current with coverage of hot topics including MRSA, neonatal pain, cardiovascular fetal interventions, care of the late preterm infant, and the developing intestinal microbiome. Tap into the fresh perspectives of new editors who provide extensive updates throughout, particularly on genetic and respiratory disorders. Apply the latest nutritional findings with thorough discussions of this valuable information in the more comprehensive nutrition section. Master the fundamentals of neonatology through the greater emphasis on developmental biology and pathobiology.
The Year Book of Neonatal and Perinatal Medicine brings you abstracts of the articles that reported the year's breakthrough developments in neontatology and perinatology, carefully selected from more than 500 journals worldwide. Dr. Avroy Fanaroff, Emeritus Professor as Case Western Reserve University, is a key opinion leader who has been a driving force in the field for many years. He authors many commentaries himself and has assembled top experts to select the most important journal articles and write commentaries that evaluate the clinical importance of each article and discuss its application to patient care. There's no faster or easier way to stay informed! This annual covers all aspects of care from the fetus, postnatal growth, labor and delivery, infectious diseases, respiratory disorders, cardiovascular health, and gastrointestinal health to name a few. The Year Book of Neonatal and Perinatal Medicine publishes annually in November.
The ONLY review book for the Neonatal-Perinatal Medicine board exam This comprehensive review for the Neonatal-Perinatel Medicine board exam includes everything test takers need for exam success: thorough concept reviews, full-color illustrations, highlighted key points, and case-based Q&A. The content is weighted to match that of the exam, so students know they are spending just the right amount of time on each topic. The authors of the book are uniquely qualified to create such as book as they currently run exam review workshops and have many years of experience preparing residents and physicians for the examination. This is a particularly valuable entry into the McGraw-Hill Medical test prep line as neonatology is the most popular pediatric subspecialty. Includes 4-color insert of neontatel dermatology and infectious disease illustrations Each chapter includes clinical vignettes with board-style Q&A
Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.
Far from a sign of healthy prosperity and contentment, overweight and obesity are now considered high risk factors for a wide range of diseases including early death and disability, heart disease, diabetes, reproductive problems, cancer, breathing problems and arthritis. Obesity, now at epidemic levels in many countries, is defined as an excessively high amount of body fat or adipose tissue in relation to lean body mass. The amount of body fat (or adiposity) includes concern for both the distribution of fat throughout the body and the size of the adipose tissue deposits. This book includes within its scope the causal connection of obesity to diseases as well as the prevention and treatment of obesity. Leading-edge scientific research from throughout the world is presented.
How the Food Industry Is Destroying Our Brains and Harming Our Children
Author: Carol Simontacchi
Category: Health & Fitness
An unprecedented and impeccably reported look at how American food manufacturers and their "products" may be endangering our minds. With obesity becoming one of the fastest-growing worldwide epidemics, and manufactured food fueling that trend, The Crazy Makers is timelier than ever. This updated edition includes a new chapter on autism, as well as revised material that illustrates just how much the industry has changed in a few short years. Based on extensive research, epidemiological evidence, and a formal study of schoolchildren's eating habits, The Crazy Makers identifies how the latest food products may be literally driving us crazy. Carol Simontacchi offers the reader nutritional primers and recipes to help counteract the problems facing us and our children every time we sit down to eat.