A Breakthrough Examination of Epidemic Antidepressant Harm and Dependence

Author: Beverley Thomson

Publisher: Hatherleigh Press


Category: Health & Fitness

Page: 240

View: 669

Overtreatment with antidepressants and underestimation of risks have left millions worldwide with complex problems and no obvious solutions or easily accessible information to guide them. They are often unaware of the harm antidepressants have caused, how their medication has impacted their lives and are oblivious to the dangers of their dependence on the medication they 'take as prescribed'. Antidepressed makes the realities of the issue of taking antidepressants easier to understand through evidence-based facts and anecdotal accounts including patient testimonies.

Physiology in Extreme Conditions: Adaptations and Unexpected Reactions

Author: Maria G. Trivella

Publisher: Frontiers Media SA




View: 680

Physiology in extreme conditions can reveal important reactions of the human body, which help our assessment of limits emerging under healthy conditions and critical signals of transition toward disease. While many mechanisms could simply be associated with adaptations, others refer to unexpected reactions in response to internal stimuli and/or external abrupt changes.

Constructive Therapies

Author: Michael F. Hoyt

Publisher: Guilford Press


Category: Psychology

Page: 340

View: 521

Recognizing that clients are unique and resourceful creators of their own realities, this hands-on guide promotes skills that help clinicians meet the demands of the current health care environment. Contributors representing a range of specialties demonstrate how they assist clients to achieve desired goals, using actual case examples that provide a vivid sense of what these noted authorities do and why they do it. Topics covered include enabling clients to draw on their own strengths and competencies; staying on track in brief therapy; asking solution-oriented questions; utilizing such techniques as role playing, reframing, story telling, acknowledgment humor, and encouragement in resolving conflict; helping clients access valuable resources that may have been compartmentalized as a result of physical or sexual abuse; supporting clients in freeing themselves from maladaptive patterns such as eating disorders; and more. Note: This book was previously published in hardcover. See the hardcover listing for the original copyright date.


King Lear Retold (Hogarth Shakespeare)

Author: Edward St Aubyn

Publisher: Random House


Category: Drama

Page: 224

View: 253

From the author of the Patrick Melrose novels, now a major Sky Atlantic television series starring Benedict Cumberbatch Henry Dunbar, the once all-powerful head of a global media corporation, is not having a good day. In his dotage he handed over care of the corporation to his two eldest daughters, Abby and Megan. But relations quickly soured, leaving him to doubt the wisdom of past decisions. Now imprisoned in a care home in the Lake District with only a demented alcoholic comedian as company, Dunbar starts planning his escape. As he flees into the hills, his family is hot on his heels. Who will find him first, his beloved youngest daughter, Florence, or the tigresses Abby and Megan, so keen to divest him of his estate?

Ordinarily Well

The Case for Antidepressants

Author: Peter D. Kramer

Publisher: Farrar, Straus and Giroux


Category: Psychology

Page: 336

View: 428

Do antidepressants work, or are they glorified dummy pills? How can we tell? In Ordinarily Well, the celebrated psychiatrist and author Peter D. Kramer examines the growing controversy about the popular medications. A practicing doctor who trained as a psychotherapist and worked with pioneers in psychopharmacology, Kramer combines moving accounts of his patients’ dilemmas with an eye-opening history of drug research to cast antidepressants in a new light. Kramer homes in on the moment of clinical decision making: Prescribe or not? What evidence should doctors bring to bear? Using the wide range of reference that readers have come to expect in his books, he traces and critiques the growth of skepticism toward antidepressants. He examines industry-sponsored research, highlighting its shortcomings. He unpacks the “inside baseball” of psychiatry—statistics—and shows how findings can be skewed toward desired conclusions. Kramer never loses sight of patients. He writes with empathy about his clinical encounters over decades as he weighed treatments, analyzed trial results, and observed medications’ influence on his patients’ symptoms, behavior, careers, families, and quality of life. He updates his prior writing about the nature of depression as a destructive illness and the effect of antidepressants on traits like low self-worth. Crucially, he shows how antidepressants act in practice: less often as miracle cures than as useful, and welcome, tools for helping troubled people achieve an underrated goal—becoming ordinarily well.

Gray Matters

Brain Injury: the Inside Perspective

Author: Heidi Lerner

Publisher: AuthorHouse


Category: Biography & Autobiography


View: 194

Intriguing Book of Poetry Published by a Brain Injury Survivor Gray Matters, Brain Injury: The Inside Perspective is a book filled with poetic insights of a woman who lived through a near-fatal brain injury. Her intimate knowledge and sense of humor can help survivors cope, as well as better understand their injuries and themselves. This book gives a personal sense or Inside Perspective of brain injury, thus enabling readers to better understand brain injury survivors. Brain injury occurs around the world in a variety of circumstances; in sports events, motor-vehicle accidents, terrorist attacks & war (and the list goes on)... According to the International Brain Injury Association, head injury is the leading cause of death and disability worldwide. Thirty percent of the soldiers that have returned from Iraq and are returning from Afghanistan have Traumatic Brain Injuries; more than two percent of the United States' population has sustained a Traumatic Brain Injury. Even with brain injury being so widespread, it is still hard to identify people living with the complications of this “invisible disability.” Ms. Lerner knows that the lack of awareness regarding brain injury makes survivors’ lives quite problematic. Writing Gray Matters was aimed at easing the integration of survivors back into the community. With a creative flair, she informs her readers about brain injury; she strikes a chord by sharing personal changes, loss and challenges, thus giving readers a sense of what it is like to walk in the shoes of a brain injury survivor. The chapters of the book cover topics including: brain injury, the symptoms of injury, rehabilitation, the brain, academic rehab, recreational therapy (including nature & the ocean's healing influence) and brain injury peer support. This book will considerably help brain injury survivors to better understand their injury and themselves, it will also aid them by being better understood by others. Gray Matters has helped family members and friends to better understand their loved ones. This book can also be a great asset to rehab professionals, by giving them a more intimate understanding of the dilemmas of a brain injury; for only when you know what an individual’s problem is, can you treat it. Gray Matters offers an articulate, introspective and sometimes humorous view of what it is like to suffer a near-fatal blow to the head and live with its complications. The author presents a thorough, subjective viewpoint as well as a professional and objective understanding of brain injury. Gray Matters presents a deeper understanding of the inner-workings of the mind and how in many ways, brain injury effects life as we know it.

The Tao of Music

Sound Psychology

Author: John M. Ortiz

Publisher: Weiser Books


Category: Music

Page: 416

View: 454

Just about everyone likes to listen to music to put them "in the mood," and these techniques get you "out" of a mood! The "Tao" part is about accepting what you're feeling, and dealing with it, by using Dr. Ortiz's methods. Includes musical menus that you can use to create your own program for dealing with issues, koans for meditation, and various other fun exercises to make music a part of your holistic health program. Appendix, bibliography, index.

Medical Proceedings

A South African Journal for the Advancement of Medical Science




Category: Clinical medicine


View: 656


Author: Sullivan Dana




Page: 280

View: 110

Nursing a baby - it's the most simple, natural thing in the world, right? Then why is it so fraught and freighted for so many women? In Unbuttoned, a collection of essays edited by Dana Sullivan and Maureen Connolly, 25 women share their thoughts and feelings about breastfeeding, all from the standpoint of personal experience. By turns enlightening, entertaining, moving, and thought provoking, their stories are sure to get readers talking. The essays are as varied as women themselves. Best - selling author Julia Glass describes nursing her two sons after being treated for breast cancer. Rebecca Walker remembers breastfeeding her seriously ill baby in the neonatal intensive care unit. And humorist Suzanne Schlosberg milks the logistics of nursing twins for laughs, while columnist Patricia Berry defends her decision to bottle - feed her three daughters. Linda Murray, editor - in - chief, contributes a thoughtful foreword. The essays are organized in a way that echoes the chronology of the nursing experience itself. In Part One, Latching On, women share their stories about starting breastfeeding; by Part Four, Letting Go, they've moved on to the sometimes - wistful, sometimes - welcome process of weaning. In these pages are laughter and tears, love and longing, tenderness and temper tantrums - and above all, a multifaceted portrait of what it means to nurture a baby. Unbuttoned makes a wonderful gift for new or expectant mothers, not to mention their partners. It's also an intriguing selection for book groups or moms' groups, who will surely find much to discuss among the essays. Even women whose nursing days are well behind (or ahead) of them will find food for thought in this insightful collection.

Altered Serotonin Regulation in Genetic and Post-Stroke Models of Anxiety and Depression

Author: Faranak Vahid-Ansari



Category: Cerebrovascular disease


View: 489

Major depression is a complex disease involving genetic and environmental factors. Previous studies suggest that functional genetic polymorphisms that alter the serotonin (5-HT) system in combination with psychosocial stress can synergistically increase the strength of these associations. In addition, depression is associated with several neurological disorders involving neuronal injury, including stroke (i.e. post-stroke depression, PSD). Both forms of depression are treated with 5-HT-selective antidepressants like fluoxetine, but remission rates do not exceed 50%. Evidence showed that alterations affecting the 5-HT system, directly or indirectly, lead to anxiety or depression phenotypes and may elucidate determinants of response to antidepressants. To better understand common and unique alterations in both genetic- and injury-related depression, I have generated and investigated two novel mouse models that exemplify a serotonin-related genetic risk (Flx-Freud-1 mice) and an injury model (ischemic lesion), to identify similarities and differences in their behavioral phenotypes, and in response to fluoxetine treatment. In the Flx-Freud-1 mouse model, 5-HT neuron-specific adult knockout of Freud-1, a key repressor of the 5-HT1A receptor gene, led to overexpression of 5-HT1A autoreceptors thought to negatively regulate the 5-HT system. These mice showed increased 5-HT1A autoreceptor responses, reduced 5-HT levels and a robust anxiety and depression phenotype that was resistant to chronic fluoxetine treatment. These behaviors were dependent on increased 5-HT1A autoreceptors since they were not seen in mice lacking 5-HT1A autoreceptors in adult Freud-1 knockout background. Instead an opposite anti-depressed phenotype emerged, suggesting that Freud-1 might have additional functions in 5-HT cells. In the PSD model, the vasoconstrictor endothelin-1 was injected to induce transient ischemia in the left medial prefrontal cortex, iv part of the circuitry thought to be damaged in PSD in humans. This stroke resulted in a persistent anxiety, depression and cognitive impairment. Chronic fluoxetine treatment alone or combined with voluntary exercise was effective to reverse the behavioral and cognitive phenotypes in this PSD mouse model.The results of genetic and SSRI treated stroke models show that changes in 5-HT system contribute to widespread dysregulation of the neuronal circuitry implicated in depression, anxiety. Genetic alteration of the 5-HT system conferred fluoxetine-resistance, while cortical stroke which indirectly altered the 5-HT system remained responsive to fluoxetine. Following unilateral stroke, there was increased activity of the contralateral hemisphere, including the prefrontal cortex and limbic areas involved in anxiety and depression, and activation of the 5-HT system. Effective treatment with chronic fluoxetine alone or combined with exercise significantly reduced and balanced the contralesional neuronal activation in affected regions that correlated with improvements in phenotypes. In conclusion, this work implicates genetic changes that directly alter the 5-HT system in resistance to chronic fluoxetine treatment. Therefore, the Flx-Freud-1-induced 5-HT1A autoreceptor overexpression mouse model may provide a useful pre-clinical model of antidepressant resistance. In contrast, in the PSD model, in which expression of 5-HT1A autoreceptors remained intact, chronic fluoxetine treatment reversed depression and anxiety phenotypes. This model may provide insight into changes in neuronal activity that allows antidepressants to mediate behavioral and cognitive improvement.

Discontinuing Antidepressant Medications

Author: Giovanni Fava

Publisher: Oxford University Press



Page: 168

View: 684

The handbook guides clinicians through the challenge of discontinuing antidepressants in their patients, by providing updated information that may help to determine if discontinuation of antidepressant drugs is feasible for a patient; what the counter-indications would be for stopping or continuing; and how discontinuation can be achieved.

Lost Connections

Author: Johann Hari

Publisher: Bloomsbury Publishing


Category: Psychology

Page: 336

View: 166

THE INTERNATIONAL BESTSELLER 'A book that could actually make us happy' SIMON AMSTELL 'This amazing book will change your life' ELTON JOHN 'One of the most important texts of recent years' BRITISH JOURNAL OF GENERAL PRACTICE 'Brilliant, stimulating, radical' MATT HAIG 'The more people read this book, the better off the world will be' NAOMI KLEIN 'Wonderful' HILLARY CLINTON 'Eye-opening' GUARDIAN 'Brilliant for anyone wanting a better understanding of mental health' ZOE BALL 'A game-changer' DAVINA MCCALL 'Extraordinary' DR MAX PEMBERTON 'Beautiful' RUSSELL BRAND Depression and anxiety are now at epidemic levels. Why? Across the world, scientists have uncovered evidence for nine different causes. Some are in our biology, but most are in the way we are living today. Lost Connections offers a radical new way of thinking about this crisis. It shows that once we understand the real causes, we can begin to turn to pioneering new solutions – ones that offer real hope.

The Secret Circuit

The Little-Known Court Where the Rules of the Information Age Unfold

Author: Bruce D. Abramson

Publisher: Rowman & Littlefield Publishers


Category: Law

Page: 416

View: 180

Imagine a high impact, low profile, nonpartisan government institution located across the street from the White House. Imagine that it plays a central role in shaping our technology industries, in overseeing globalization, and in holding the federal government responsible for its commercial activities. Imagine that only Congress and the Supreme Court can correct its mistakes. Such an institution exists. The United States Court of Appeals for the Federal Circuit was born in the early 1980s as part of the drive to liberalize and reinvigorate the American economy. Over the past twenty-five years, it has earned its nickname as the 'patent court' by revolutionizing American patent law, but it also oversees international trade law and government business law. Taken together, its docket covers the rules guiding innovation, globalization, and much of government. Are these rules impelling the economy forward or holding it back? Are the policies we have the policies we want? How are we faring, as the economy transitions from the industrial age to the information age? What responsibility does the Federal Circuit bear in shaping America's current economic policies in these three critical areas? The Secret Circuit demystifies this Court's work and answers these questions.

Sacrament of Lies

Author: Elizabeth Dewberry

Publisher: Penguin


Category: Fiction

Page: 272

View: 320

When Grayson Guillory's mother died, she helped her father get rid of the empty vodka and pill bottles next to the body. It wouldn't do for the governor of Louisiana to have a wife who committed suicide after years of mental illness—especially just as he’s contemplating the presidency. Grayson's husband—her father's speechwriter—helps him keep the story quiet, and the family doctor makes sure the cause of death will be listed as a heart attack. But Grayson has a problem. When she thought she was helping her father cover up a suicide, she might actually have been covering up a murder. Because Grayson's mother left a videotape hidden among her personal effects in which she claims her life is in danger. Of course, Grayson's mother did suffer from paranoid delusions. And maybe Grayson does too: manic depression is a highly hereditary illness. But just because she’s paranoid doesn't mean they're not out to get her...

Molecules of Emotion

Why You Feel the Way You Feel

Author: Candace B. Pert

Publisher: Simon and Schuster


Category: Psychology

Page: 368

View: 625

Explains the science behind the brain's opiate receptors and other evidence of the intimate connections between mind and body, and their meaning for the future of Western medicine