Population Genetics and Microevolutionary Theory

Author: Alan R. Templeton

Publisher: John Wiley & Sons

ISBN: 0470047216

Category: Science

Page: 720

View: 9231

The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

Population Genetics and Microevolutionary Theory

Author: Alan R. Templeton

Publisher: Wiley-Liss

ISBN: 9780471409519

Category: Science

Page: 720

View: 8540

The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

Human Population Genetics

Author: John H. Relethford

Publisher: John Wiley & Sons

ISBN: 111818162X

Category: Science

Page: 296

View: 6158

Introductory guide to human population genetics and microevolutionary theory Providing an introduction to mathematical population genetics, Human Population Genetics gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study. Thorough and accessible, Human Population Genetics presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain theories central to the field. By describing changes in the frequency of genetic variants from one generation to the next, this book hones in on the mathematical basis of evolutionary theory. Human Population Genetics includes: Helpful formulae for learning ease Graphs and analogies that make basic points and relate the evolutionary process to mathematical ideas Glossary terms marked in boldface within the book the first time they appear In-text citations that act as reference points for further research Exemplary case studies Topics such as Hardy-Weinberg equilibrium, inbreeding, mutation, genetic drift, natural selection, and gene flow Human Population Genetics solidifies knowledge learned in introductory biological anthropology or biology courses and makes it applicable to genetic study. NOTE: errata for the first edition can be found at the author's website: http://employees.oneonta.edu/relethjh/HPG/errata.pdf

Migration and Colonization in Human Microevolution

Author: Alan G. Fix

Publisher: Cambridge University Press

ISBN: 9780521592062

Category: Science

Page: 236

View: 9453

An integrative approach linking the causes of migration to genetic consequences for human evolution.

Tinkering

The Microevolution of Development

Author: Novartis Foundation

Publisher: John Wiley & Sons

ISBN: 9780470319406

Category: Science

Page: 300

View: 2610

Much recent research in evolutionary developmental biology has focused on the origin of new body plans. However, most evolutionary change at the population and species level consists of tinkering: small-scale alterations in developmental pathways within a single body plan. Such microevolutionary events have been well studied on a population genetic level and from the perspective of adaptive phenotypic evolution, but their developmental mechanisms remain poorly studied. This book explores both theoretical and practical issues of tinkering. It features a wide range of perspectives to address several fundamental questions. How does tinkering occur developmentally, and how is it manifested phenotypically? Are the developmental mechanisms by which tinkering occur different from those that underlie larger evolutionary changes? What are the developmental constraints on tinkering? And how do we test hypotheses about microevolutionary shifts in development from the fossil record? With contributions from experts in a range of fields, this fascinating book makes exciting reading for anyone studying evolution, developmental biology or genetics.

Genetics and Evolution of Infectious Diseases

Author: Michel Tibayrenc

Publisher: Elsevier

ISBN: 0128001534

Category: Medical

Page: 686

View: 833

Genetics and Evolution of Infectious Diseases, Second Edition, discusses the constantly evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world. Students in public health, biomedical professionals, clinicians, public health practitioners, and decisions-makers will find valuable information in this book that is relevant to the control and prevention of neglected and emerging worldwide diseases that are a major cause of global morbidity, disability, and mortality. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases during the last century, in recent decades the world has witnessed a worldwide human immunodeficiency virus (HIV) pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. The economic, social, and political burden of infectious diseases is most evident in developing countries which must confront the dual burden of death and disability due to infectious and chronic illnesses. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field of infectious disease

Principles of Population Genetics

Author: Daniel L. Hartl,Andrew G. Clark

Publisher: Sinauer Associates Incorporated

ISBN: 9780878933082

Category: Science

Page: 652

View: 9005

This edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level.

Coalescent Theory

An Introduction

Author: John Wakeley

Publisher: Roberts Publishers

ISBN: 9780974707754

Category: Medical

Page: 326

View: 4246

"An introduction to coalescent theory, which provides the foundation for molecular population genetics and genomics. Coalescent theory is the conceptual framework for studies of DNA sequence variation within species, and is the source of essential tools for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data"--Provided by publisher.

Genetics and the Origin of Species

Author: Theodosius Dobzhansky,Theodosius Grigorievich Dobzhansky

Publisher: Columbia University Press

ISBN: 9780231054751

Category: Science

Page: 364

View: 354

Featuring an introduction by Stephen Jay Gould, "Genetics and the Origin of Species" presents the first edition of Dobzhansky's groundbreaking and now classic inquiry into what has emerged as the most important single area of scientific inquiry in the twentieth century: biological theory of evolution. Genetics and the Origin of Species went through three editions (1937, 1941, and 1951) in which the importance accorded natural selection changed radically.

Microbial Population Genetics

Author: Jianping Xu

Publisher: Horizon Scientific Press

ISBN: 190445559X

Category: Science

Page: 213

View: 6736

Microbial population genetics is a rapidly advancing field of investigation with relevance to many areas of science. The subject encompasses theoretical issues, such as the origins and evolution of species, sex, and recombination. Population genetics lays the foundations for tracking the origin and evolution of antibiotic resistance and deadly infectious pathogens and is also an essential tool in the utilization of beneficial microbes. This invaluable book, written by leading researchers in the field, details the current major advances in microbial population genetics and genomics. Distinguished international scientists introduce fundamental concepts, describe genetic tools, and comprehensively review recent data from SNP surveys, whole-genome DNA sequences, and microarray hybridizations. The chapters cover broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa, and algae. A major focus is the application of molecular tools in the study of genetic variation. Topics covered include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens, and metagenomics. Microbial Population Genetics is an essential volume for everyone interested in population genetics, and it is highly recommended reading for all microbiologists.

Mathematical population genetics

Author: Warren John Ewens

Publisher: Springer

ISBN: 9783540095774

Category: Mathematics

Page: 325

View: 7436

Jacob's Legacy

A Genetic View of Jewish History

Author: David B. Goldstein

Publisher: Yale University Press

ISBN: 0300145101

Category: Science

Page: 176

View: 3149

Who are the Jews? Where did they come from? What is the connection between an ancient Jewish priest in Jerusalem and today's Israeli sunbather on the beaches of Tel Aviv? These questions stand at the heart of this engaging book. Geneticist David Goldstein analyzes modern DNA studies of Jewish populations and examines the intersections of these scientific findings with the history (both biblical and modern) and oral tradition of the Jews. With a special gift for translating complex scientific concepts into language understandable to all, Goldstein delivers an accessible, personal, and fascinating book that tells the history of a group of people through the lens of genetics. In a series of detective-style stories, Goldstein explores the priestly lineage of Jewish males as manifested by Y chromosomes; the Jewish lineage claims of the Lemba, an obscure black South African tribe; the differences in maternal and paternal genetic heritage among Jewish populations; and much more. The author also grapples with the medical and ethical implications of our rapidly growing command of the human genomic landscape. The study of genetics has not only changed the study of Jewish history, Goldstein shows, it has altered notions of Jewish identity and even our understanding of what makes a people a people.

Population Genetics

A Concise Guide

Author: John H. Gillespie

Publisher: JHU Press

ISBN: 9781421401706

Category: Science

Page: 232

View: 6034

This book is indispensable for students working in a laboratory setting or studying free-ranging populations.

Atlas of Mammalian Chromosomes

Author: Stephen J. O'Brien,Joan C. Menninger,William G. Nash

Publisher: John Wiley & Sons

ISBN: 0471779040

Category: Science

Page: 544

View: 8347

A stunning visual collection of the banded metaphase chromosome karyotypes from some 850 species of mammals, the Atlas of Mammalian Chromosomes represents an unabridged compendium of the state of this genomic art form. Bringing together information currently scattered throughout the cytogenetics literature for scores of published and unpublished species, this atlas features high-quality karyotype images for nearly every mammal studied to date, making it the most comprehensive assemblage of high-resolution chromosome photographs available--a critically invaluable resource for today's comparative genomics era. For every available species, the Atlas of Mammalian Chromosomes presents the best karyotype produced, the common and Latin name of the species, the published citation, and the contributing authors. Most karyotypes are G-banded, revealing the chromosomal bar codes of homologous segments among related species. Addressing the mandate of the Human Genome Project to annotate the genomes of other organisms as well, the Atlas of Mammalian Chromosomes offers a step forward in our understanding of species formation, of genome organization, and of DNA script for natural selection. It is an invaluable resource for geneticists, mammalogists, and biologists interested in comparative genomics, systematics, and chromosome structure.

Understanding Population Genetics

Author: Torbjörn Säll,Bengt O. Bengtsson

Publisher: John Wiley & Sons

ISBN: 1119124034

Category: Science

Page: 278

View: 3880

Interpretations, extensions and comments -- Altruism and natural selection via individuals and groups -- Frequency-dependent selection and resource competition -- Rare allele advantage due to infections and self-incompatibility -- Questions -- Chapter 9 Selection on a quantitative trait -- Analysis -- Selection in quantitative genetics -- Selection in population genetics - one more time -- Notations and assumptions -- Combining the tools -- Summing up -- Interpretations, extensions and comments -- The genetic effect of selection on a quantitative trait -- The limits of selection and the nature of -- Threshold selection and disease liability -- Quantitative genetics is not suited for causal analyses -- Chapter 10 Evolutionary genetic analysis of the sex ratio -- Analysis -- Assumptions and notations -- Finding the recursion equation system -- Testing for stability -- Summing up -- Interpretations, extensions and comments -- Sex ratio selection -- An explanation of well-delimited validity -- Meiotic recombination is an evolved genetic system -- Evolutionary genetic analysis -- What's next? -- Estimates and tests in population genetics -- The mutation-selection balance -- Partial genetic isolation -- Segregation distortion and genetic conflicts -- Epilogue -- Thanks -- Glossary -- Answers -- References -- Index -- EULA

The Structure of Evolutionary Theory

Author: Stephen Jay Gould

Publisher: Harvard University Press

ISBN: 0674417925

Category: Science

Page: 1464

View: 2574

The world’s most revered and eloquent interpreter of evolutionary ideas offers here a work of explanatory force unprecedented in our time—a landmark publication, both for its historical sweep and for its scientific vision. With characteristic attention to detail, Stephen Jay Gould first describes the content and discusses the history and origins of the three core commitments of classical Darwinism: that natural selection works on organisms, not genes or species; that it is almost exclusively the mechanism of adaptive evolutionary change; and that these changes are incremental, not drastic. Next, he examines the three critiques that currently challenge this classic Darwinian edifice: that selection operates on multiple levels, from the gene to the group; that evolution proceeds by a variety of mechanisms, not just natural selection; and that causes operating at broader scales, including catastrophes, have figured prominently in the course of evolution. Then, in a stunning tour de force that will likely stimulate discussion and debate for decades, Gould proposes his own system for integrating these classical commitments and contemporary critiques into a new structure of evolutionary thought. In 2001 the Library of Congress named Stephen Jay Gould one of America’s eighty-three Living Legends—people who embody the “quintessentially American ideal of individual creativity, conviction, dedication, and exuberance.” Each of these qualities finds full expression in this peerless work, the likes of which the scientific world has not seen—and may not see again—for well over a century.

Macroevolution

Explanation, Interpretation and Evidence

Author: Emanuele Serrelli,Nathalie Gontier

Publisher: Springer

ISBN: 3319150456

Category: Science

Page: 403

View: 6364

This book is divided in two parts, the first of which shows how, beyond paleontology and systematics, macroevolutionary theories apply key insights from ecology and biogeography, developmental biology, biophysics, molecular phylogenetics and even the sociocultural sciences to explain evolution in deep time. In the second part, the phenomenon of macroevolution is examined with the help of real life-history case studies on the evolution of eukaryotic sex, the formation of anatomical form and body-plans, extinction and speciation events of marine invertebrates, hominin evolution and species conservation ethics. The book brings together leading experts, who explain pivotal concepts such as Punctuated Equilibria, Stasis, Developmental Constraints, Adaptive Radiations, Habitat Tracking, Turnovers, (Mass) Extinctions, Species Sorting, Major Transitions, Trends and Hierarchies – key premises that allow macroevolutionary epistemic frameworks to transcend microevolutionary theories that focus on genetic variation, selection, migration and fitness. Along the way, the contributing authors review ongoing debates and current scientific challenges; detail new and fascinating scientific tools and techniques that allow us to cross the classic borders between disciplines; demonstrate how their theories make it possible to extend the Modern Synthesis; present guidelines on how the macroevolutionary field could be further developed; and provide a rich view of just how it was that life evolved across time and space. In short, this book is a must-read for active scholars and because the technical aspects are fully explained, it is also accessible for non-specialists. Understanding evolution requires a solid grasp of above-population phenomena. Species are real biological individuals and abiotic factors impact the future course of evolution. Beyond observation, when the explanation of macroevolution is the goal, we need both evidence and theory that enable us to explain and interpret how life evolves at the grand scale.

Human Natures

Genes, Cultures, and the Human Prospect

Author: Paul R. Ehrlich

Publisher: Island Press

ISBN: 9781559637794

Category: Science

Page: 531

View: 9636

Explores the impact and inconsistancies of human evolution upon human nature, examining the physical, intellectual, cultural, and sexual aspects of human development and behaviors in the light of current scientific theory.

Microevolution Rate, Pattern, Process

Author: Andrew P. Hendry,Michael T. Kinnison

Publisher: Springer Science & Business Media

ISBN: 9401005850

Category: Science

Page: 535

View: 5378

From guppies to Galapagos finches and from adaptive landscapes to haldanes, this compilation of contributed works provides reviews, perspectives, theoretical models, statistical developments, and empirical demonstrations exploring the tempo and mode of microevolution on contemporary to geological time scales. New developments, and reviews, of classic and novel empirical systems demonstrate the strength and diversity of evolutionary processes producing biodiversity within species. Perspectives and theoretical insights expand these empirical observations to explore patterns and mechanisms of microevolution, methods for its quantification, and implications for the evolution of biodiversity on other scales. This diverse assemblage of manuscripts is aimed at professionals, graduate students, and advanced undergraduates who desire a timely synthesis of current knowledge, an illustration of exciting new directions, and a springboard for future investigations in the study of microevolution in the wild.

Genes in populations

Author: Eliot B. Spiess

Publisher: Wiley-Interscience

ISBN: 9780471849735

Category: Science

Page: 774

View: 5252

In this revised and updated edition of the comprehensive population genetics book, treatment extends basic genetic principles to the dynamics of genes and genotypes in groups of interbred individuals. Presents three points of view: evolutionary, quantitative, and medical/anthropological. Considers random mating, non-random mating, and evolutionary forces that can change gene and genotype frequencies over time. The impact of DNA sequencing is adressed and illustrative examples from the experimental literature are included.