Population Genetics

A Concise Guide

Author: John H. Gillespie

Publisher: JHU Press

ISBN:

Category: Science

Page: 232

View: 315

This book is indispensable for students working in a laboratory setting or studying free-ranging populations.

Population Genetics

A Concise Guide

Author: John H. Gillespie

Publisher:

ISBN:

Category: Science

Page: 174

View: 392

"In a species with a million individuals," writes John H. Gillespie, "it takes roughly a million generations for genetic drift to change allele frequencies appreciably. There is no conceivable way of verifying that genetic drift changes allele frequencies in most natural populations. Our understanding that it does is entirely theoretical. Most population geneticists are not only comfortable with this state of affairs, but revel in the fact that they can demonstrate on the back of an envelope, rather than in the laboratory, how an important evolutionary force operates." Longer than the back of an envelope but more concise than many books on the subject, this brief introduction to the field of population genetics offers students and researchers an overview of a discipline that is of growing importance. Chapter topics include genetic drift; natural selection; non-random mating, quantitative genetics; and the evolutionary advantage of sex. While each chapter treats a specific topic or problem in genetics, the common thread throughout the book is what Gillespie calls "the main obsession of our field," the recurring question, "Why is there so much genetic variation in natural populations?" "Population genetics remains the central intellectual connection between genetics and evolution. As genetics becomes integral to all aspects of biology, the unifying nature of evolutionary studies rests more and more on population genetics. This book lays out much of the foundation of population genetics augmented with interesting particulars and conceptual insight. Population genetics involves ideas that are quantitative and often difficult for biology undergraduates, but Professor Gillespie offershis characteristically clear thinking and articulate explanations." -- Charles Langley, University of California-Davis

Understanding Population Genetics

Author: Torbjörn Säll

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 278

View: 594

Interpretations, extensions and comments -- Altruism and natural selection via individuals and groups -- Frequency-dependent selection and resource competition -- Rare allele advantage due to infections and self-incompatibility -- Questions -- Chapter 9 Selection on a quantitative trait -- Analysis -- Selection in quantitative genetics -- Selection in population genetics - one more time -- Notations and assumptions -- Combining the tools -- Summing up -- Interpretations, extensions and comments -- The genetic effect of selection on a quantitative trait -- The limits of selection and the nature of -- Threshold selection and disease liability -- Quantitative genetics is not suited for causal analyses -- Chapter 10 Evolutionary genetic analysis of the sex ratio -- Analysis -- Assumptions and notations -- Finding the recursion equation system -- Testing for stability -- Summing up -- Interpretations, extensions and comments -- Sex ratio selection -- An explanation of well-delimited validity -- Meiotic recombination is an evolved genetic system -- Evolutionary genetic analysis -- What's next? -- Estimates and tests in population genetics -- The mutation-selection balance -- Partial genetic isolation -- Segregation distortion and genetic conflicts -- Epilogue -- Thanks -- Glossary -- Answers -- References -- Index -- EULA

Human Population Genetics

Author: John H. Relethford

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 296

View: 482

"Human Population Genetics will provide an introduction to mathematical population genetics, along with relevant examples from human (and some non-human primate) populations, and will also present concepts and methods of population genetics that are specific to the study of human populations. The purpose of this book is to provide a basic background text for advanced undergraduate and graduate students interesting in the mechanisms of human microevolution"--

توقيع في الخلية

الدنا وأدلة التصميم الذكي

Author: د. ستيفن ماير

Publisher: مركز براهين للأبحاث والدراسات

ISBN:

Category:

Page: 736

View: 823

في (توقيع في الخلية) يطرح ماير أول مرجع شامل لحجة التصميم الذكي المبنية على الدنا. بينما يروي قصة نجاح محاولات حل خيوط اللغز الذي لم يتعرض له داروين –كيف نشأت الحياة؟–، طور ماير حجة للنظرية التي غالبا ما يساء فهمها، مستخدما الطريقة التي استعملها داروين نفسه. بطرحه لرؤية جديدة لواحد من الألغاز المستمرة للبيولوجيا الحديثة، أثبت ماير أن أدلة التصميم الذكي ليست قائمة على الجهل أو رفض العلم، بل هي بالأحرى قائمة على أدلة علمية ساحقة، تتزايد مع الوقت. «حجة حاسمة مبنية على نقاط علمية مذهلة من أحدث ما توصل إليه العلم». - د. فيليب سكيل (بروفيسور شرفي في جامعة ولاية بنسلفانيا وعضو الأكاديمية الوطنية للعلوم) «استعراض رائع... سواءً أكنت تؤيد التصميم الذكي أو تعارضه، كتاب (توقيع في الخلية) هو كتابٌ يجب أن تقرأه». - د. سكوت ترنر (بروفيسور البيولوجيا البيئية وبيولوجيا الغابات في جامعة ولاية نيويورك) «عرض متقن للإشكالية الصعبة». - د. توماس ناجل (أستاذ بجامعة نيويورك)، في جريدة Times Literary Supplement

Clinical Genetics in Nursing Practice

Third Edition

Author: Felissa R. Lashley, PhD, RN, FABMGG

Publisher: Springer Publishing Company

ISBN:

Category: Medical

Page: 584

View: 370

Designated a Doody's Core Title! The third edition of this award-winning text provides new and updated knowledge about genetics issues relevant to nursing practice. Read in sequence or used as a reference, this is a comprehensive overview of how genetics affetcs the care that nurses provide. In addition to a summary of basic human genetics and discussion of the Human Genome Project, this new edition includes the latest research findings and implications about inheritance, major genetic disorders (cytogenetics or chromosomal, inherited biochemical, and congenital anomalies), and genetics in twin studies. A consideration of the ethical impact of genetics on society and future generations, as well as information on assisted reproduction round out the overview. Includes over 100 illustrations and photos of specific genetic disorders; tables and figures on the distribution of disease; and an extensive appendix listing associations, organizations, and websites relevant to genetics.

Genetics

Laboratory Investigations

Author: Thomas Robert Mertens

Publisher:

ISBN:

Category: Science

Page: 281

View: 169

THE definitive genetics lab manual for over 50 years, this user-friendly volume stresses classical genetics, but includes some of the recent advances related to molecular and human genetics as well. Drosophila and Maize Experiments in Genetics: Monohybrid Crosses; Dihybrid Crosses. Cell Reproduction: Mitosis. Meiosis in Animals: Oogenesis and Spermatogenesis. Meiosis in Angiosperms: Microsporogenesis and Megasporogenesis. Polytene Chromosomes from Drosophila Salivary Glands. Sex Chromosomes and Gene Transmission. The Sex Check: A Study of Sex Chromatin in Human Cells. Human Chromosomes. Linkage and Crossing Over. Genetics of Ascospore Color in Sordaria: An Investigation of Linkage and Crossing Over Using Tetrad Analysis. Open-Ended Experiments Using Drosophila: Locating a Mutant Gene in Its Chromosome. Isolation of DNA. Restriction Endonuclease Digestion and Gel Electrophoresis of DNA. Amplification of DNA Polymorphisms by Polymerase Chain Reaction (PCR) and DNA Fingerprinting. Transformation of Escherichia coli. Gene Action: Synthesis of ... b-Galactosidase in Escherichia coli. Chromatographic Characterization of Drosophila melanogaster Mutants. Bacterial Mutagenesis. Gene Recombination in Phage. Polygenic Inheritance: Fingerprint Ridge Count. Population Genetics: The Hardy-Weinberg Principle; The Effects of Selection and Genetic Drift. Applied Human Genetics.

Nature encyclopedia of the human genome

Author: Nature Publishing Group

Publisher: Natures Pub Ltd

ISBN:

Category: Medical

Page: 5159

View: 277

Nature Encyclopedia of the Human Genome is the only reference resource devoted entirely to the scientific basis and genetics and genomics research and the complex commercial, philosophical, and ethical questions that arise from it. It presents a comprehensive and rigorously detailed overview of current genome science and its groundbreaking applications, examining the many topics that surround the field from the differing perspectives of history, philosophy, ethics, law, medicine, public health, and industry. Core areas covered include: structural genomics, functional genomics, chromosome structure and function, evolution and comparative genomics, genome mapping and sequencing, genes and disease, behavioural and psychiatric genetics, mathematical and population genetics, proteomics, bioinformatics, ethical, legal and social issues and biographies or key figures.