"As will be seen, there is not much missing here. I thought that the sections were well balanced, with rarely too much or too little on a given topic...This is a text to be welcomed by both teachers and students." BIOCHEMISTRY & MOLECULAR BIOLOGY EDUCATION (on the first edition) The second edition of this successful textbook explains the basic principles behind the key techniques currently used in the modern biochemical laboratory and describes the pros and cons of each technique and compares one to another. It is non-mathematical, comprehensive and approachable for students who are not physical chemists. A major update of this comprehensive, accessible introduction to physical biochemistry. Includes two new chapters on proteomics and bioinformatics. Introduces experimental approaches with a minimum of mathematics and numerous practical examples. Provides a bibliography at the end of each chapter. Written by an author with many years teaching and research experience, this text is a must-have for students of biochemistry, biophysics, molecular and life sciences and food science.
Biophotonics in dentistry is a rapidly growing area. Unlike other books, this invaluable compendium touches on the fundamental areas in biophotonics. Contributed by world-renowned authors, it provides a basic understanding on a range of topics for individuals of different backgrounds to acquire a minimum knowledge of research and development in biophotonics. The chapters are arranged in two major categories. The first describes the fundamental aspects of photonics, such as photomechanics, biomedical imaging, lasers and laser-tissue interaction, spectroscopy and photodynamic therapy. The second details the applications of biophotonics, with special relevance to dentistry, including dental photobiomechanics, Raman spectroscopy and dental tissue optics. Contents:PhotomechanicsBiomedical ImagingSpectroscopyLasers and Laser Tissue InteractionMechanisms and Applications of Photodynamic TherapyDental Photo-BiomechanicsMicro-Raman Spectroscopy: Principles and Applications in Dental ResearchDental and Oral Tissue OpticsFiber Optic Diagnostic Sensors Readership: Researchers, academics and graduate students of biophotonics in dentistry. Keywords:Biophotonics;Photomechanics;Bioimaging;Spectroscopy;DentistryKey Features:A comprehensive textbook ideal for a course on photonics in dentistryProvides an in-depth introduction to light-tissue interactions
The Second Edition of Principles of Physical Biochemistry provides the most current look at the theory and techniques used in the study of the physical chemistry of biological and biochemical molecules--including discussion of mass spectrometry and single-molecule methods. As leading experts in biophysical chemistry, these well-known authors offer unique insights and coverage not available elsewhere. Physical techniques currently used by practicing biochemists, including new chapters dedicated to extended material on mass spectrometry and single-molecule methods are included. The book's streamlined organization groups all hydrodynamic methods in Chapter 5 and combines Raman spectroscopy with the spectroscopy section. Relevant problems and applications help readers develop critical-thinking skills that they can apply to real biochemical and biological situations facing professionals in the industry. Biological Macromolecules; Thermodynamics and Biochemistry; Molecular Thermodynamics; Statistical Thermodynamics; Methods for the Separation and Characterization of Macromolecules; X-Ray Diffraction; Scattering From Solutions of Macromolecules; Quantum Mechanics and Spectroscopy; Absorption Spectroscopy; Linear and Circular Dichroism; Emission Spectroscopy; Nuclear Magnetic Resonance Spectroscopy; Macromolecules in Solution: Thermodynamics and Equilibria; Chemical Equilibria Involving Macromolecules; Mass Spectrometry of Macromolecules; Single-Molecule Methods. A useful reference for biochemistry professionals or for anyone interested in learning more about biochemistry.
This full-colour undergraduate textbook, based on a two semestercourse, presents the fundamentals of biological physics,introducing essential modern topics that include cells, polymers,polyelectrolytes, membranes, liquid crystals, phase transitions,self-assembly, photonics, fluid mechanics, motility, chemicalkinetics, enzyme kinetics, systems biology, nerves, physiology, thesenses, and the brain. The comprehensive coverage, featuring in-depth explanations ofrecent rapid developments, demonstrates this to be one of the mostdiverse of modern scientific disciplines. The Physics of Living Processes: A Mesoscopic Approach iscomprised of five principal sections: • Building Blocks • Soft Condensed Matter Techniques in Biology • Experimental Techniques • Systems Biology • Spikes, Brains and the Senses The unique focus is predominantly on the mesoscale —structures on length scales between those of atoms and themacroscopic behaviour of whole organisms. The connections betweenmolecules and their emergent biological phenomena provide a novelintegrated perspective on biological physics, making this animportant text across a variety of scientific disciplines includingbiophysics, physics, physical chemistry, chemical engineering andbioengineering. An extensive set of worked tutorial questions are included,which will equip the reader with a range of new physical tools toapproach problems in the life sciences from medicine,pharmaceutical science and agriculture.
The most comprehensive reference on fluorescent nanodiamond physical and chemical properties and contemporary applications Fluorescent nanodiamonds (FNDs) have drawn a great deal of attention over the past several years, and their applications and development potential are proving to be manifold and vast. The first and only book of its kind, Fluorescent Nanodiamonds is a comprehensive guide to the basic science and technical information needed to fully understand the fundamentals of FNDs and their potential applications across an array of domains. In demonstrating the importance of FNDs in biological applications, the authors bring together all relevant chemistry, physics, materials science and biology. Nanodiamonds are produced by powerful cataclysmic events such as explosions, volcanic eruptions and meteorite impacts. They also can be created in the lab by high-pressure high-temperature treatment of graphite or detonating an explosive in a reactor vessel. A single imperfection can give a nanodiamond a specific, isolated color center which allows it to function as a single, trapped atom. Much smaller than the thickness of a human hair, a nanodiamond can have a huge surface area that allows it to bond with a variety of other materials. Because of their non-toxicity, nanodiamonds may be useful in biomedical applications, such as drug delivery and gene therapy. The most comprehensive reference on a topic of rapidly increasing interest among academic and industrial researchers across an array of fields Includes numerous case studies and practical examples from many areas of research and industrial applications, as well as fascinating and instructive historical perspectives Each chapter addresses, in-depth, a single integral topic including the fundamental properties, synthesis, mechanisms and functionalisation of FNDs The first book published by the key patent holder with his research group in the field of FNDs Fluorescent Nanodiamonds is an important working resource for a broad range of scientists and engineers in industry and academia. It will also be a welcome reference for instructors in chemistry, physics, materials science, biology and related fields.
The Physical Basis of Biochemistry is a rigorous, imaginative textbook that applies physical and chemical principles to understanding the bi ology of cells. The book features numerous problem sets and examples, clear illustrations, and extensive appendices that provide additional information on mathematics, physics and chemistry topics that support the text. The Physical Basis of Biochemistry is suitable for graduate and advanced undergraduate courses in physical biochemistry, biophysic al chemistry, and physical chemistry with application in the life scie nces. It will be welcomed by instructors seeking a text which combines a quantitative approach with a consistent biological perspective.
Principles and Applications in Biological Sciences
Author: Ignacio Tinoco
Publisher: Pearson College Division
This best-selling volume presents the principles and applications of physical chemistry as they are used to solve problems in biology and medicine. The First Law; the Second Law; free energy and chemical equilibria; free energy and physical Equilibria; molecular motion and transport properties; kinetics: rates of chemical reactions; enzyme kinetics; the theory and spectroscopy of molecular structures and interactions: molecular distributions and statistical thermodynamics; and macromolecular structure and X-ray diffraction. For anyone interested in physical chemistry as it relates to problems in biology and medicine.
Principles and Applications of ESR Spectroscopy fills the gap between the detailed monographs in ESR spectroscopy and the general textbooks in molecular physics, physical chemistry, biochemistry or spectroscopy. The latter only briefly explain the underlying theory and do not provide details about applications, while the currently available ESR textbooks are primarily focused on the technique as such. This text is based upon the authors’ long experience of teaching the subject to a mixed audience, in the extreme case ranging from physics to biology. The potential of the method is illustrated with applications in fields such as molecular science, catalysis and environmental sciences, polymer and materials sciences, biochemistry and radiation chemistry/physics. Theoretical derivations have in general been omitted, as they have been presented repeatedly in previous works. The necessary theory is instead illustrated by practical examples from the literature.
Cell separation is at the core of current methods in experimental biology and medicine. Its importance is illustrated by the large number of physical and biochemical principles that have been evaluated for application to cell separation. The development of cell separation methods is driven by the needs of biological and medical research, and the ever-increasing demands for sensitivity, selectivity, yield, timeliness and economy of the process. The interdisciplinary nature of research in this area and the volume of information available in research publications and conferences necessitates a basic description of the fundamental processes involved in magnetic cell separation that may help the user in navigating this wealth of information available online and in scientific publications. This book will appeal to researchers in many areas utilizing this technique, including those working in cell biology, clinical research, inorganic chemistry, biochemistry, chemical engineering, materials science, physics and electrical engineering. Provides examples of how to calculate the volume magnetic susceptibility, a fundamental quantity for calculating the magnetic force acting on a cell, from various types of magnetic susceptibilities available in literature Introduces the elements of magnetostatics as they apply to cell magnetization and the magnetization of magnetic micro- and nano- particles used for cell separation Describes the parameters used to determine cell magnetophoresis