Selected Topics

Author: B. Hamprecht,V. Neuhoff

Publisher: Springer Science & Business Media

ISBN: 3642709400

Category: Medical

Page: 213

View: 5119

Intestinal Transport

Fundamental and Comparative Aspects

Author: M. Gilles-Baillien,R. Gilles

Publisher: Springer Science & Business Media

ISBN: 3642691099

Category: Science

Page: 378

View: 6475

The aim of this symposium was to provide a framework for fruitful discussion on intestinal transport, not only for advanced scientists but also for younger people starting in this field of research. Invited lectures, communications and poster presentations were focused on four central themes, all treating the prop erties of the sole intestinal epithelium, deliberately leaving aside problems dealing with more integrative functions of the whole intestine. The importance of motility or blood circulation, for instance, is certainly capital in the overall intestinal function, but these aspects by themselves deserve another meeting. This volume has compiled the manuscripts of the invited lectures which sub stantially comprised the four sessions of the Symposium. Part 1 is designed to emphasize actual knowledge of the transport of water, inorganic as well as organic ions and molecules across the isolated intestinal epithelium. An enormous wave of investigations has emerged from studies per formed with "Ussing chambers", which roused interest in studies on absorption mechanisms and subsequently on secretory processes. This has triggered off a trend to research on isolated cells as absorption and secretion are the main func tion of the different cell types constituting the intestinal epithelium. In this first session not only the importance of the parallel arrangement of these different cellular entities is stressed, but also the role played by the paracellular route.

Current Catalog

Author: National Library of Medicine (U.S.)

Publisher: N.A


Category: Medicine

Page: N.A

View: 968

First multi-year cumulation covers six years: 1965-70.

Molecular Aspects of Inflammation

42. Colloquium der Gesellschaft für Biologische Chemie 11.-13. April 1991 in Mosbach/Baden

Author: Helmut Sies,Leopold Flohe,Guido Zimmer

Publisher: Springer Science & Business Media

ISBN: 3642764126

Category: Science

Page: 288

View: 4597

Understanding the molecular basis of complex biological processes has been amajor goal of biological chemistry from early on. Inflammation is such one entitiy, and recent years have seen exciting progress in the understanding of molecuar interactions; there has been a long way from dolor, rubor, calor and tumor as a fundamental description of the phenomenon tocurrent knowlegde on e.g. the control of the respiratory burst of the granulocyte, the atomic details of protease regulation, or the interaction of cytokines. The book is organized in the order of increasing complexity, starting out with the key phenomena of the inflammatory response and its modulation by cytokines to intravascular events and shock and sepsis; thus, the current attemptsto apply basic knowledge on mediators of inflam- mation to the clinical situation were also considered.

Concepts and Models

Author: D.C. Tosteson

Publisher: Springer Science & Business Media

ISBN: 3642463703

Category: Medical

Page: 540

View: 493

This Volume forms the cornerstone of this series of four books on Membrane Transport in Biology. It includes chapters that address i) the theoretical basis of investigations of transport processes across biological membranes, ii) some of the experimental operations often used by scientists in this field, iii) chemical and biological properties common to most biological membranes, and iv) planar thin lipid bilayers as models for biological membranes. The themes developed in these chapters recur frequently throughout the entire series. Transport of molecules across biological membranes is a special case of diffu sion and convection in liquids. The conceptual frame of reference used by investigators in this field derives, in large part, from theories of such processes in homogeneous phases. Examples of the application of such theories to transport across biological membranes are found in Chapters 2 and 4 of this Volume. In Chapter 2, Sten-Knudsen emphasizes a statistical and molecular approach while, in Chapter 4 Sauer makes heavy use of the thermodynamics of irreversi ble processes. Taken together, these contributions introduce the reader to the two sets of ideas which have dominated the thinking of scientists working in this field. Theoretical consideration of a more special character are also included in several other Chapters in Volume I. For example, Ussing (Chapter 3) re-works the flux ratio equation which he introduced into the field of transport across biological membranes in 1949.

Photoreceptor Optics

Author: A.W. Snyder,R. Menzel

Publisher: Springer Science & Business Media

ISBN: 3642809340

Category: Science

Page: 526

View: 9231

The above consideration indicates that at present many of the experi mental facts on PS in animals can be quantitatively explained within the limits of the "universal" photoreceptor membrane concept. Of course, existence of preferential orientation of the absorbing dipoles in the tubuli of the rhabdomeres can not be totally rejected. We hope that the concept of the "universal" photoreceptor membrane may serve as the useful instrument when dealing with newly discovered properties of visual cells so that true mechanisms of electrical and optical coupling will be searched for instead of assumptions being made on additional properties of the photoreceptor membrane in every new animal under study. 5. Absorption Spectrum of the Universal Photoreceptor Membrane and Spectral Sensitivity of the Photoreceptor 5. 1 Preliminary Notes It seems nearly self-evident that the absorption spectrum of the pho toreceptor membrane coincides exactly with that of the visual pigment it contains. Hence, the membrane must exhibit three bands of absorp tion - the principal band with its peak within the limits of visible spectrum (or a-peak); the secondary band between 340 and 380 nm (S peak); and the third, protein band, in the ultraviolet (UV) at 280 nm (COLLINS et al. , 1952). The main peak of absorption is located within the range 433-575 nm for retinol-based pigments and between 438 and 620 nm for 3-dehydroretinol-based pigments, the position of Amax de pending on many ecological factors.

Biochemistry of Differentiation and Morphogenesis

Author: L. Jaenicke

Publisher: Springer Science & Business Media

ISBN: 3642688330

Category: Science

Page: 304

View: 8945

The topic of this Mosbach Colloquium was meant as a question to begin with. When I started to study differentiation and morphogenesis in Volvox I hoped for a straightforward answer along prepared groove- only to find out that also here things follow Murphy's Law: they were much more complicated than expected! Succour had to be sought. Thus, the idea arose to put this question before a board of experts. Experience would have warned any ex-service man never to utter an idea or else you would be made responsible, and it came as it had to come: I was made impressario of this gremium; I had to assemble the experts. These Proceedings contain their expertise. I cannot even say that I biased it by my picking. In the beginning I aimed at setting different accents by inclination and force of habit. Then, by trial and error, by advice and declination, the programme shaped itself. It eventually gained momentum of which also the size of this volume is indicative. In this volume are printed all the papers presented - with two regret ted exceptions - but not the sometimes lively discussion, which clari fied and pruned here and there. It would just have made the size too unwieldy. Differentiation and morphogenesis start with the expression of genes. The development programme reels off the genome and is regulated by the position of the appropriate genes. Their structure is in the focus of gene biochemistry since the decisive tools have become available.

Index of Conference Proceedings Received

Annual cumulation

Author: British Library. Document Supply Centre

Publisher: N.A


Category: Congresses and conventions

Page: N.A

View: 9563

Regulation of Transcription and Translation in Eukaryotes

Author: Ekkehard K.F. Bautz,P. Karlson,H. Kersten

Publisher: Springer Science & Business Media

ISBN: 3642657257

Category: Science

Page: 352

View: 1106

This volume represents the proceedings of the 24th Mos bach Colloquium on "Regulation of Transcription and Trans lation in Eukaryotes" which was held April 26-28, 1973, in Mosbach, Germany, under the auspices of the Gesellschaft fiir Biologische Chemie. To the three of us (H. KERSTEN, P. KARLSON and myself) who were commissioned with the invitation of speakers, it was a difficult decision as to whether we should attempt to cover with some twenty contributions as many aspects of this broad topic as possible, or to sacrifice the intellectually perhaps more pleasing but more specula tive concepts and to concentrate on a few aspects of gene expression in reasonable detail. We unanimously decided on the latter course, leaving such important and timely topics as for example, hormone action, cyclic AMP and reverse transcription to the proceedings of other symposia, and con centrating on the four questions which are most basic to an understanding of the mechanisms of transcription and trans lation and for which fragmentary but nonetheless reliable experimental results have become available within the last few years. These are the structure of chromatin, the syn thesis of messenger RNA, the structure of the active ribo some, and the role of initiation factors in protein synthesis.

Glyco-and Cellbiology

Biosynthesis, Transport, and Function of Glycoconjugates

Author: Felix Wieland,Werner Reutter

Publisher: Springer Science & Business Media

ISBN: 3642787290

Category: Science

Page: 194

View: 9724

Understanding the biological role of the diverse oligosaccharides of glycoproteins and glycolipids has been a major challenge in cell biology. Glycosylation is an essential step during molecular recognition and is involved in protein folding, sorting, targeting and intracellular translocation. Further, glycoproteins of the cell membrane play a major role in cell adhesion, hormone function, antibody action and signal mediation. Current knowledge of the molecular and cellular mechanisms involved in these processes is presented.