Molecular Population Genetics

Author: Matthew William Hahn

Publisher: Sinauer Associates, Incorporated

ISBN: 9780878939657

Category:

Page: 352

View: 8080

Molecular Population Genetics is a general text covering one of the most active and exciting areas in biology. Combining advances in molecular biology and genomics with mathematical and empirical findings from population genetics, work in molecular population genetics has uncovered the extraordinary history of natural selection and demographic shifts in many organisms, including humans. While basic descriptions of the methods and tools of this field can be found in disparate places, no previous book has brought them together in a single volume. Rather than cobble together pieces from books, reviews, and primary research articles, Molecular Population Genetics presents a coherent user's guide to the field. Intended as a text for upper-level undergraduate and graduate students, the book will also be useful as a detailed reference for active professionals.

Molecular Population Genetics, Evolutionary Biology, and Biological Conservation of Neotropical Carnivores

Author: Manuel Ruiz-Garcia,Joseph Mark Shostell

Publisher: Nova Science Pub Incorporated

ISBN: 9781624170713

Category: Science

Page: 720

View: 5166

The neotropical ecoregion consisting of South America, Central America, Southern Mexico, the Caribbean Islands, and Southern Florida, has long been considered an area rich in mammalian diversity and one that contains some of the worlds iconic carnivores such as the Jaguar and Puma. These, and other carnivores represent the highest trophic levels within neotropical areas and as keystone species, can markedly alter omnivore and herbivore mammalian communities and indirectly, plant communities. Unfortunately, due to human population pressures, many neotropical areas and the mammals within them are increasingly at risk. This problem is compounded by the lack of current genetics, evolutionary biology and conservation data of these critical carnivores available to conservation biologists at the forefront of trying to preserve and protect these imperiled geographical areas. This book helps to meet these shortcomings by providing contributions from 60 of the worlds leading scientists in the area of neotropical carnivores. The first section of the book covers molecular population genetics and phylogeography of diverse neotropical carnivores such as otters, coatis and other Mustelidae and Procyonidae, wild cats (jaguar, puma, ocelot, jaguarondi, Pampas cat, and Andean cat) and the Andean bear. Significant sections of the book are also devoted to the topics of reproduction, geometric morphometrics of wild canids and a complete paleontological view of the evolution of all neotropical carnivore groups. Furthermore, the book contains several chapters on the conservation details and varying cultural perspectives regarding the two larger and more mythical neotropical carnivores, the jaguar and the Andean bear, which together, are the paradigm for the conservation programs in Central and South America.

Population Genetics and Microevolutionary Theory

Author: Alan R. Templeton

Publisher: John Wiley & Sons

ISBN: 0470047216

Category: Science

Page: 720

View: 6213

The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

Population Genetics, Molecular Evolution, and the Neutral Theory

Selected Papers

Author: Motoo Kimura

Publisher: University of Chicago Press

ISBN: 9780226435626

Category: Science

Page: 686

View: 9254

One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.

Computational Molecular Evolution

Author: Ziheng Yang

Publisher: Oxford University Press

ISBN: 0198566999

Category: Medical

Page: 357

View: 1365

This book describes the models, methods and algorithms that are most useful for analysing the ever-increasing supply of molecular sequence data, with a view to furthering our understanding of the evolution of genes and genomes.

Molecular Evolution and Population Genetics for Marine Biologists

Author: Yuri Kartavtsev

Publisher: CRC Press

ISBN: 1498701612

Category: Science

Page: 363

View: 2121

Research in modern experimental and theoretical population genetics has been strengthened by advances in molecular techniques for the analysis of genetic variability. The evolutionary relationships of organisms may be investigated by comparing DNA sequences. This book covers chapters on population genetics, DNA polymorphism, genetic homeostasis, and biochemical genetics, plus a chapter on phylogenetic tree construction. In addition, each chapter contains training materials with numerical examples.

Population Genetics, Molecular Evolution, and the Neutral Theory

Selected Papers

Author: Motoo Kimura

Publisher: University of Chicago Press

ISBN: 9780226435626

Category: Science

Page: 686

View: 6820

One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.

Microbial Population Genetics

Author: Jianping Xu

Publisher: Horizon Scientific Press

ISBN: 190445559X

Category: Science

Page: 213

View: 4802

Microbial population genetics is a rapidly advancing field of investigation with relevance to many areas of science. The subject encompasses theoretical issues, such as the origins and evolution of species, sex, and recombination. Population genetics lays the foundations for tracking the origin and evolution of antibiotic resistance and deadly infectious pathogens and is also an essential tool in the utilization of beneficial microbes. This invaluable book, written by leading researchers in the field, details the current major advances in microbial population genetics and genomics. Distinguished international scientists introduce fundamental concepts, describe genetic tools, and comprehensively review recent data from SNP surveys, whole-genome DNA sequences, and microarray hybridizations. The chapters cover broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa, and algae. A major focus is the application of molecular tools in the study of genetic variation. Topics covered include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens, and metagenomics. Microbial Population Genetics is an essential volume for everyone interested in population genetics, and it is highly recommended reading for all microbiologists.

Population Genetics

Author: Matthew Hamilton

Publisher: John Wiley & Sons

ISBN: 1444362453

Category: Science

Page: 424

View: 1887

This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.

Elements of Evolutionary Genetics

Author: Brian Charlesworth

Publisher: Roberts Publishers

ISBN: N.A

Category: Science

Page: 734

View: 7000

Evolutionary genetics considers the causes of evolutionary change and the nature of variability in evolution. The methods of evolutionary genetics are critically important for the analysis and interpretation of the massive datasets on DNA sequence variation and evolution that are becoming available, as well for our understanding of evolution in general. This book shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data. The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure. The final two chapters demonstrate how the theory illuminates our understanding of the evolution of breeding systems, sex ratios and life histories, and some aspects of genome evolution.

Human Population Genetics

Author: John H. Relethford

Publisher: John Wiley & Sons

ISBN: 0470464674

Category: Science

Page: 296

View: 4063

"Human Population Genetics will provide an introduction to mathematical population genetics, along with relevant examples from human (and some non-human primate) populations, and will also present concepts and methods of population genetics that are specific to the study of human populations. The purpose of this book is to provide a basic background text for advanced undergraduate and graduate students interesting in the mechanisms of human microevolution"--

Principles of Population Genetics

Author: Daniel L. Hartl,Andrew G. Clark

Publisher: Sinauer Associates Incorporated

ISBN: 9780878933082

Category: Science

Page: 652

View: 6759

This edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level.

Evolution and Selection of Quantitative Traits

Author: Bruce Walsh,Michael Lynch

Publisher: Oxford University Press

ISBN: 0192566644

Category: Science

Page: 1504

View: 5618

Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.

Population Genetics

A Concise Guide

Author: John H. Gillespie

Publisher: JHU Press

ISBN: 9781421401706

Category: Science

Page: 232

View: 2769

This book is indispensable for students working in a laboratory setting or studying free-ranging populations.

Molecular Approaches to Fundamental and Applied Entomology

Author: John Oakeshott,Max J. Whitten

Publisher: Springer Science & Business Media

ISBN: 1461392179

Category: Science

Page: 498

View: 6479

Insects as a group occupy a middle ground in the biosphere between bacteria and viruses at one extreme, amphibians and mammals at the other. The size and general nature of insects present special problems to the study of entomology. For example, many commercially available instruments are geared to measure in grams, while the forces commonly encountered in studying insects are in the milligram range. Therefore, techniques developed in the study of insects or in those fields concerned with the control of insect pests are often unique. Methods for measuring things are common to all sciences. Advances sometimes depend more on how something was done than on what was measured; indeed a given field often progresses from one technique to another as new methods are discovered, developed, and modified. Just as often, some of these techniques find their way into the classroom when the problems involved have been sufficiently ironed out to permit students to master the manipulations in a few laboratory periods. Many specialized techniques are confined to one specific research laboratory. Although methods may be considered commonplace where they are used, in another context even the simplest procedures may save considerable time. It is the purpose of this series (1) to report new developments in methodology, (2) to reveal sources of groups who have dealt with and solved particular entomological problems, and (3) to describe experiments which may be applicable for use in biology laboratory courses.

Understanding Population Genetics

Author: Torbjörn Säll,Bengt O. Bengtsson

Publisher: John Wiley & Sons

ISBN: 1119124034

Category: Science

Page: 278

View: 3298

Interpretations, extensions and comments -- Altruism and natural selection via individuals and groups -- Frequency-dependent selection and resource competition -- Rare allele advantage due to infections and self-incompatibility -- Questions -- Chapter 9 Selection on a quantitative trait -- Analysis -- Selection in quantitative genetics -- Selection in population genetics - one more time -- Notations and assumptions -- Combining the tools -- Summing up -- Interpretations, extensions and comments -- The genetic effect of selection on a quantitative trait -- The limits of selection and the nature of -- Threshold selection and disease liability -- Quantitative genetics is not suited for causal analyses -- Chapter 10 Evolutionary genetic analysis of the sex ratio -- Analysis -- Assumptions and notations -- Finding the recursion equation system -- Testing for stability -- Summing up -- Interpretations, extensions and comments -- Sex ratio selection -- An explanation of well-delimited validity -- Meiotic recombination is an evolved genetic system -- Evolutionary genetic analysis -- What's next? -- Estimates and tests in population genetics -- The mutation-selection balance -- Partial genetic isolation -- Segregation distortion and genetic conflicts -- Epilogue -- Thanks -- Glossary -- Answers -- References -- Index -- EULA

A Primer of Population Genetics

Author: Daniel L. Hartl

Publisher: Sinauer Associates Incorporated

ISBN: 9780878933044

Category: Science

Page: 221

View: 8125

In response to many requests, the Third Edition of A Primer of Population Genetics has been dramatically shortened and streamlined for greater accessibility. Designed primarily for undergraduates, it will also serve for graduate students and professionals in biology and other sciences who desire a concise but comprehensive overview of the field with a primary focus on the integration of experimental results with theory. The abundance of experimental data generated by the use of molecular methods to study genetic polymorphisms sparked a transformation in the field of population genetics. Present in virtually all organisms, molecular polymorphisms allow populations to be studied without regard to species or habitat, and without the need for controlled crosses, mutant genes, or for any prior genetic studies. Thus a familiarity with population genetics has become essential for any biologist whose work is at the population level. These fields include evolution, ecology, systematics, plant breeding, animal breeding, conservation and wildlife management, human genetics, and anthropology. Population genetics seeks to understand the causes of genetic differences within and among species, and molecular biology provides a rich repertoire of techniques for identifying these differences.