Microbial-based Polyhydroxyalkanoates

Author: Amirul Al-Ashraf Abdullah

Publisher: Smithers Rapra

ISBN: 1909030643

Category: Science

Page: 190

View: 3042

Polyhydroxyalkanoate (PHA) is a group of natural biopolymers synthesised by a wide variety of microbial genera. It is a biodegradable and biocompatible thermoplastic consisting of a repeated chain of various hydroxyalkanoate monomers.PHA is envisioned to be one of the most prospective and futuristic materials which is beneficial to mankind and to the world. In current world trends which concerns at the sustainable development from renewable and eco-friendly resources, PHA has garnered a growing attention as an alternative to petroleum based plastics.The book comes with two main objectives. In this book, major pipelines in processing this beneficial biopolymer were first reviewed from upstream to the downstream. The upstream processing includes the isolation of PHA producers, biosynthesis of PHA, genetic modification of PHA producers and optimisation of PHA production; meanwhile the downstream processing covers the PHA recovery and purification, degradation, quantification, characterisation, as well as the application of PHA. Readers will be exposed to the introductory information, along with some necessary concepts behind each subject.The second objective of this book is to provide readers with the recent advances on each PHA processing field. Being updated with the recent findings, this will provide an insight to readers on how the research trends for each subject are evolving from time to time. These updates will become useful case studies and quick references to readers from various areas, either from academia or industry.

Advances in Polyhydroxyalkanoate (PHA) Production

Author: Martin Koller

Publisher: MDPI

ISBN: 3038426377

Category: Science

Page: 258

View: 9568

This book is a printed edition of the Special Issue "Advances in Polyhydroxyalkanoate (PHA) Production" that was published in Bioengineering

Recent Advances in Biotechnology Volume, 1: Microbial Biopolyester Production, Performance and Processing Microbiology, Feedstocks, and Metabolism

Author: Martin Koller

Publisher: Bentham Science Publishers

ISBN: 1681083256

Category: Science

Page: 500

View: 5355

Global plastic production is estimated to be over 300Mt annually. Most conventional plastics are predominantly produced from fossil fuels and are highly resistant to biodegradation, and only a small share of about 20% of spent plastics is believed to be recycled, which is a cause for environmental concern. Biodegradable plastics would solve this concern as they are a sustainable alternative, yet these do not even cover 5% of the global plastic market. Microbial polyhydroxyalkanoates (PHAs) are a versatile group of polyesters produced by nature as prokaryotic storage materials. PHAs can be produced through sustainable bioprocess engineering and have displayed remarkable flexibility in their physical and chemical properties. PHAs are the subject of several scientific papers and numerous PHA patents have also been filed, generating significant interest in the plastic production industry. To develop overall sustainable and efficient production processes, all bioprocess steps need to be thoroughly understood and accounted for. These processes start with the selection of suitable inexpensive raw materials (microbes and enzymes), optimizing the process engineering and process regime, and conclude with the enhancement of product recovery in terms of time, energy, and material input. Microbial Biopolyester Production, Performance and Processing: Microbiology, Feedstocks, and Metabolism encompasses eight chapters that cover aspects of the microbiology and biotechnology of producing biodegradable plastics. The contents focus on the selection of powerful archaeal and eubacterial production strains, genetic engineering as a tool for optimized PHA production and inexpensive carbon sources for microbial cultures. The volume is a useful resource for bioprocess engineers, microbiologists, biotechnologists and chemical engineers interested in the basics of biodegradable plastic production. Recent Advances in Biotechnology is a book series comprising of peer-reviewed reference works and monographs that compile the latest developments in the field of biotechnology. Each volume has a thematic focus and features topical reviews written by experts. The series will highlight multidisciplinary perspectives to interested readers (biotechnologists, microbiologists, bioprocess engineers, agronomists, medical professionals, sustainability researchers etc.)

Recent Advances in Biotechnology Volume, 2: Microbial Biopolyester Production, Performance and Processing Bioengineering, Characterization, and Sustainability

Author: Martin Koller

Publisher: Bentham Science Publishers

ISBN: 1681083736

Category: Science

Page: 520

View: 3599

Global plastic production is estimated to be over 300Mt annually. Most conventional plastics are predominantly produced from fossil fuels and are highly resistant to biodegradation, and only a small share of about 20% of spent plastics is believed to be recycled, which is a cause for environmental concern. Biodegradable plastics would solve this concern as they are a sustainable alternative, yet these do not even cover 5% of the global plastic market. Microbial polyhydroxyalkanoates (PHAs) are a versatile group of polyesters produced by nature as prokaryotic storage materials. PHAs can be produced through sustainable bioprocess engineering and have displayed remarkable flexibility in their physical and chemical properties. PHAs are the subject of several scientific papers and numerous PHA patents have also been filed, generating significant interest in the plastic production industry. To develop overall sustainable and efficient production processes, all bioprocess steps need to be thoroughly understood and accounted for. These processes start with the selection of suitable inexpensive raw materials (microbes and enzymes), optimizing the process engineering and process regime, and conclude with the enhancement of product recovery in terms of time, energy, and material input. Microbial Biopolyester Production, Performance and Processing: Bioengineering, Characterization, and Sustainability is a compilation of eight chapters covering bacterial polyesters, green plastics and PHAs from various angles. The contents of this volume focus on sustainable practices focus on the sustainability of processes that involve the synthesis and recycling of these meterials. The volume is a useful resource for bioprocess engineers, microbiologists, biotechnologists and chemical engineers interested in the basics of biodegradable plastic production.

Comprehensive Biotechnology

Author: N.A

Publisher: Newnes

ISBN: 0080885047

Category: Science

Page: 5320

View: 5079

The second edition of Comprehensive Biotechnology continues the tradition of the first inclusive work on this dynamic field with up-to-date and essential entries on the principles and practice of biotechnology. The integration of the latest relevant science and industry practice with fundamental biotechnology concepts is presented with entries from internationally recognized world leaders in their given fields. With two volumes covering basic fundamentals, and four volumes of applications, from environmental biotechnology and safety to medical biotechnology and healthcare, this work serves the needs of newcomers as well as established experts combining the latest relevant science and industry practice in a manageable format. It is a multi-authored work, written by experts and vetted by a prestigious advisory board and group of volume editors who are biotechnology innovators and educators with international influence. All six volumes are published at the same time, not as a series; this is not a conventional encyclopedia but a symbiotic integration of brief articles on established topics and longer chapters on new emerging areas. Hyperlinks provide sources of extensive additional related information; material authored and edited by world-renown experts in all aspects of the broad multidisciplinary field of biotechnology Scope and nature of the work are vetted by a prestigious International Advisory Board including three Nobel laureates Each article carries a glossary and a professional summary of the authors indicating their appropriate credentials An extensive index for the entire publication gives a complete list of the many topics treated in the increasingly expanding field

Bioprocessing for Value-Added Products from Renewable Resources

New Technologies and Applications

Author: Shang-Tian Yang

Publisher: Elsevier

ISBN: 9780080466712

Category: Technology & Engineering

Page: 684

View: 1582

Bioprocessing for Value-Added Products from Renewable Resources provides a timely review of new and unconventional techniques for manufacturing high-value products based on simple biological material. The book discusses the principles underpinning modern industrial biotechnology and describes a unique collection of novel bioprocesses for a sustainable future. This book begins in a very structured way. It first looks at the modern technologies that form the basis for creating a bio-based industry before describing the various organisms that are suitable for bioprocessing - from bacteria to algae - as well as their unique characteristics. This is followed by a discussion of novel, experimental bioprocesses, such as the production of medicinal chemicals, the production of chiral compounds and the design of biofuel cells. The book concludes with examples where biological, renewable resources become an important feedstock for large-scale industrial production. This book is suitable for researchers, practitioners, students, and consultants in the bioprocess and biotechnology fields, and for others who are interested in biotechnology, engineering, industrial microbiology and chemical engineering. ·Reviews the principles underpinning modern industrial biotechnology ·Provides a unique collection of novel bioprocesses for a sustainable future ·Gives examples of economical use of renewable resources as feedstocks ·Suitable for both non-experts and experts in the bioproduct industry

Advances in Polyhydroxyalkanoate (PHA) Production

Author: Martin Koller

Publisher: MDPI

ISBN: 3038426377

Category: Science

Page: 258

View: 7081

This book is a printed edition of the Special Issue "Advances in Polyhydroxyalkanoate (PHA) Production" that was published in Bioengineering

Plastics from Bacteria

Natural Functions and Applications

Author: George Guo-Qiang Chen

Publisher: Springer Science & Business Media

ISBN: 9783642032875

Category: Science

Page: 450

View: 2471

Due to the possibility that petroleum supplies will be exhausted in the next decades to come, more and more attention has been paid to the production of bacterial pl- tics including polyhydroxyalkanoates (PHA), polylactic acid (PLA), poly(butylene succinate) (PBS), biopolyethylene (PE), poly(trimethylene terephthalate) (PTT), and poly(p-phenylene) (PPP). These are well-studied polymers containing at least one monomer synthesized via bacterial transformation. Among them, PHA, PLA and PBS are well known for their biodegradability, whereas PE, PTT and PPP are probably less biodegradable or are less studied in terms of their biodegradability. Over the past years, their properties and appli- tions have been studied in detail and products have been developed. Physical and chemical modifications to reduce their cost or to improve their properties have been conducted. PHA is the only biopolyester family completely synthesized by biological means. They have been investigated by microbiologists, molecular biologists, b- chemists, chemical engineers, chemists, polymer experts, and medical researchers for many years. PHA applications as bioplastics, fine chemicals, implant biomate- als, medicines, and biofuels have been developed. Companies have been est- lished for or involved in PHA related R&D as well as large scale production. It has become clear that PHA and its related technologies form an industrial value chain in fermentation, materials, feeds, and energy to medical fields.

Process Scale Purification of Antibodies

Author: Uwe Gottschalk

Publisher: John Wiley & Sons

ISBN: 1119126916

Category: Medical

Page: 752

View: 9217

Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification. • Updates existing topics and adds new ones that include purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing • Presents new and updated discussions of different purification technologies, focusing on how they can address the capacity crunch in antibody purification • Emphasizes antibodies and innovative chromatography methods for processing

Biotechnologies and Biomimetics for Civil Engineering

Author: Fernando Pacheco Torgal,J. A. Labrincha,M. V. Diamanti,C.-P. Yu,H. K. Lee

Publisher: Springer

ISBN: 3319092871

Category: Technology & Engineering

Page: 437

View: 2399

Putting forward an innovative approach to solving current technological problems faced by human society, this book encompasses a holistic way of perceiving the potential of natural systems. Nature has developed several materials and processes which both maintain an optimal performance and are also totally biodegradable, properties which can be used in civil engineering. Delivering the latest research findings to building industry professionals and other practitioners, as well as containing information useful to the public, ‘Biotechnologies and Biomimetics for Civil Engineering’ serves as an important tool to tackle the challenges of a more sustainable construction industry and the future of buildings.

The Metabolic Pathway Engineering Handbook

Fundamentals

Author: Christina Smolke

Publisher: CRC Press

ISBN: 9781439802977

Category: Medical

Page: 678

View: 6140

This first volume of the Metabolic Pathway Engineering Handbook provides an overview of metabolic pathway engineering with a look towards the future. It discusses cellular metabolism, including transport processes inside the cell and energy generating reactions, as well as rare metabolic conversions. This volume also explores balances and reaction models, the regulation of metabolic pathways, and genome scale and multiscale modeling tools. It also covers developing appropriate hosts for metabolic engineering including the use of Escherichia coli, yeast, Bacillus Subtilis, Streptomyces, filamentous fungi, and mammalian cells using cell culture. Christine Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer’s yeast, is regarded as one of the most brilliant new minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metabolic pathway engineering. With a wealth of cutting edge research and analysis, this work also serves as an invaluable resource for those seeking to add their own contributions. Organized by topic, this 3000 page reference is available as two volumes that can be purchased individually or as a set. For information on the complete handbook visit Cat No. 3923

Industrial Biotechnology

Products and Processes

Author: Christoph Wittmann

Publisher: John Wiley & Sons

ISBN: 3527341811

Category: Science

Page: 640

View: 2482

The latest volume in the Advanced Biotechnology series provides an overview of the main product classes and platform chemicals produced by biotechnological processes today, with applications in the food, healthcare and fine chemical industries. Alongside the production of drugs and flavors as well as amino acids, bio-based monomers and polymers and biofuels, basic insights are also given as to the biotechnological processes yielding such products and how large-scale production may be enabled and improved. Of interest to biotechnologists, bio and chemical engineers, as well as those working in the biotechnological, chemical, and food industries.

Biopolyesters

Author: Wolfgang Babel,Alexander Steinbüchel

Publisher: Springer

ISBN: 3540400214

Category: Technology & Engineering

Page: 342

View: 3970

Living systems synthesize seven different classes of polymers. They provide structure and form for cells and organisms, function as catalysts and energy storage and carry the genetic information. All these polymers possess technically interesting properties. Some of these biopolymers are already used commercially. This special volume of Advances in Biochemical Engineering/Biotechnology comprises 10 chapters. It gives an overview of the water insoluble biopolyesters, in particular of the microbially synthesized poly-hydroxyalkanoate (PHA) family. It reports the state of the art of metabolism, regulation and genetic background, the latest advances made in genetic optimization of bacteria, "construction" of transgenic plants and in vitro synthesis by means of purified enzymes. Furthermore, it describes relevant technologies and evaluates perspectives concerning increasing the economic viability and competitiveness of PHA and discusses applications in medicine, packaging, food and other fields.

Environmental Microbiology for Engineers, Second Edition

Author: Volodymyr Ivanov

Publisher: CRC Press

ISBN: 1498702155

Category: Science

Page: 413

View: 3783

Updated Edition Includes a New Chapter and Enhanced Study Material The second edition of Environmental Microbiology for Engineers explores the role that microorganisms play in the engineered protection and enhancement of an environment. Offering a perfect balance of microbiological knowledge and environmental biotechnology principles, it provides a practical understanding of microorganisms and their functions in the environment and in the environmental engineering systems. The book also presents a quantitative description of applied microbiological processes and their engineering design. This updated edition adds a new chapter on construction biotechnology, as well as a new quiz, tutorial banks, and exam questions with solutions to aid readers with performing the design calculations needed and to enhance understanding of the material. The book covers essential topics that include: Diversity and functions of microorganisms in environmental engineering systems Environmental bioengineering processes Applied microbial genetics and molecular biology Microbiology of water and wastewater treatment Biotreatment of solid waste and soil bioremediation Microbial monitoring of environmental engineering systems Biocorrosion and biodeterioration of materials Biocementation and bioclogging of soil Biopollution of indoor environment Biofouling of facilities, and more Environmental Microbiology for Engineers provides a practical understanding of microorganisms in the civil engineering process and their functions in the environmental engineering systems, and is designed for practicing environmental engineers working in the areas of wastewater, solid waste treatment, soil remediation and ground improvement.

Microbial Biomass Process Technologies and Management

Author: Basanta Kumara Behera,Ajit Varma

Publisher: Springer

ISBN: 3319539132

Category: Medical

Page: 306

View: 3613

This book describes how microbes can be used as effective and sustainable resources to meet the current challenge of finding suitable and economical solutions for biopharmaceuticals, enzymes, food additives, nutraceuticals, value added biochemicals and microbial fuels, and discusses various aspects of microbial regulatory activity and its applications. It particularly focuses on the design, layout and other relevant issues in industrial microbe applications. Moreover, it discusses the entire microbial-product supply chain, from manufacturing sites to end users, both in domestic and international markets, providing insights into the global marketing of microbes and microbial biomass-derived products. Further, it includes topics concerning the effective production and utilization of eco-friendly biotechnology industries. It offers a valuable, ready-to-use guide for technologists and policymakers developing new biotechnologies.

Bioreactors

Design, Operation and Novel Applications

Author: Carl-Fredrik Mandenius

Publisher: John Wiley & Sons

ISBN: 3527683372

Category: Science

Page: 520

View: 5100

In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries. Combining theory and practice, the authors explain such leading-edge technologies as single-use bioreactors, bioreactor simulators, and soft sensor monitoring, and discuss novel applications, such as stem cell production, process development, and multi-product reactors, using case studies from academia as well as from industry. A final section addresses the latest trends, including culture media design and systems biotechnology, which are expected to have an increasing impact on bioreactor design. With its focus on cutting-edge technologies and discussions of future developments, this handbook will remain an invaluable reference for many years to come.

Allies and Enemies

How the World Depends on Bacteria

Author: Anne Maczulak

Publisher: FT Press

ISBN: 9780132119306

Category: Education

Page: 224

View: 2652

Bacteria are invisible, mysterious, deadly, self-sufficient…and absolutely essential for all life, including yours. No other living things combine their elegant simplicity with their incredibly complex role: Bacteria keep us alive, supply our food, and regulate our biosphere. We can’t live a day without them, and no chemical, antibiotic, or irradiation has ever successfully eradicated them. They’re our partners, like it or not--even though some of them will happily kill us. Allies and Enemies tells the story of this amazing, intimate partnership. Authored by Anne Maczulak, a microbiologist who’s hunted and worked with an extraordinary array of bacteria, this book offers a powerful new perspective on Earth’s oldest creatures. You’ll discover how bacteria work, how they evolve, their surprising contributions and uses, the roles they’ve played in human history, and why you can't survive without them. No form of life is more important, and in Maczulak’s hands, none is more fascinating. Outlasted, outnumbered, outsmarted They’ve been here four billion years--and they even outnumber you in your own body How bacteria keep you alive… …and how to keep them from killing you “Humans Defeat Germs!” But not for long… The Invisible Universe The stunning hidden relationships between bacteria and the rest of nature

Biodegradable Polyesters

Author: Stoyko Fakirov

Publisher: John Wiley & Sons

ISBN: 3527656979

Category: Technology & Engineering

Page: 368

View: 2146

Collating otherwise hard-to-get and recently acquired knowledge in one work, this is a comprehensive reference on the synthesis, properties, characterization, and applications of this eco-friendly class of plastics. A group of internationally renowned researchers offer their first-hand experience and knowledge, dealing exclusively with those biodegradable polyesters that have become increasingly important over the past two decades due to environmental concerns on the one hand and newly-devised applications in the biomedical field on the other. The result is an unparalleled overview for the industrial chemist and materials scientist, as well as for developers and researchers in industry and academia alike.

The Oncogene and Tumour Suppressor Gene Factsbook

Author: Robin Hesketh

Publisher: Elsevier

ISBN: 9780080538006

Category: Medical

Page: 608

View: 6817

The Second Edition of The Oncogene and Tumour Suppressor Gene FactsBook has been completely revised, updated, and expanded by 60%. The book contains more than 80 entries on oncogenes including JUN, MYC, and RAS, as well as DNA tumour viruses, tumour suppressor genes, including p53, retinoblastoma, BRCA1, BRCA2, VHL, F2FL, and essential material on angiogenesis and metastasis, apoptosis, cell cycle control, and gene therapy. Includes much new data on this fast-moving field, including newly discovered oncogenes Summarizes the clinical association and molecular properties of all known oncogenes and tumor suppression genes Contains more than 2000 terms for reference and further research Revised to included signaling pathways, apoptosis, and metastasis

Construction Biotechnology

Biogeochemistry, Microbiology and Biotechnology of Construction Materials and Processes

Author: Volodymyr Ivanov,Viktor Stabnikov

Publisher: Springer

ISBN: 9811014450

Category: Technology & Engineering

Page: 317

View: 1834

This book presents the first comprehensive text on construction biomaterials and bioprocesses. It details aspects of construction biotechnology, a new interdisciplinary area involving applications of environmental and industrial microbiology and biotechnology in geotechnical and civil engineering. It also critically reviews all existing and potential construction biotechnology processes. It discusses a number of topics including the biotechnological production of new construction materials such as self-healing concrete, construction biocomposites, construction bioplastics, and biotechnological admixtures to cement. It also addresses construction-related processes like biocementation, bioclogging, soil surface fixation and biosealing, microbial cements and grouts, the biocoating of construction material surfaces, the microbiology and biosafety of the construction environment, the prevention of biocorrosion as well as biodeterioration and biofouling in civil engineering. Biomediated precipitation of calcium, magnesium, and iron compounds as carbonates, phosphates, sulphides, and silicate minerals in soil for its clogging and strengthening are considered from geotechnical, chemical, and microbiological points of view. It offers an overview of the basic microbiology that will enable civil engineers to perform the construction biogeochemical processes. Design principles and considerations for different field implementations are discussed from a practical point of view. The book can be used as a textbook for graduate and senior undergraduate students in biotechnology, civil engineering and environmental engineering as well as a reference book for researchers and practitioners working in this new interdisciplinary area.