An Introduction to Population Genetics

Theory and Applications

Author: Rasmus Nielsen,Montgomery Slatkin

Publisher: Sinauer Associates Incorporated

ISBN: 9781605351537

Category: Science

Page: 287

View: 9147

"A text for a one-semester course in population genetics. It introduces students to classical population genetics (in terms of allele and haplotype frequencies) and modern population genetics (in terms of coalescent theory). It presents numerous applications of population genetic methods to practical problems, including testing for natural selection, detecting genetic hitchhiking and inferring the history of populations"--Provided by publisher.

Introduction to Population Genetics

Author: Richard Halliburton

Publisher: Benjamin-Cummings Publishing Company

ISBN: 9780130163806

Category: Science

Page: 650

View: 7870

Making the theory of population genetics relevant to readers, this book explains the related mathematics with a logical organization.It presents the quantitative aspects of population genetics, and employs examples of human genetics, medical evolution, human evolution, and endangered species.For an introduction to, and understanding of, population genetics.

An Introduction to Population Genetics Theory

Author: James F. Crow,Motoo Kimura

Publisher: N.A

ISBN: 9781932846126

Category: Mathematics

Page: 591

View: 1897

Originally published in 1970, this classic in the field of population genetics opens with elementary concepts and deals primarily with natural populations and less fully with the rather similar problems that arise in breeding livestock and cultivated plants.

Introduction to Theoretical Population Genetics

Author: Thomas Nagylaki

Publisher: Springer Science & Business Media

ISBN: 364276214X

Category: Science

Page: 369

View: 3083

This book covers those areas of theoretical population genetics that can be investigated rigorously by elementary mathematical methods. I have tried to formulate the various models fairly generally and to state the biological as sumptions quite explicitly. I hope the choice and treatment of topics will en able the reader to understand and evaluate detailed analyses of many specific models and applications in the literature. Models in population genetics are highly idealized, often even over idealized, and their connection with observation is frequently remote. Further more, it is not practicable to measure the parameters and variables in these models with high accuracy. These regrettable circumstances amply justify the use of appropriate, lucid, and rigorous approximations in the analysis of our models, and such approximations are often illuminating even when exact solu tions are available. However, our empirical and theoretical limitations justify neither opaque, incomplete formulations nor unconvincing, inadequate analy ses, for these may produce uninterpretable, misleading, or erroneous results. Intuition is a principal source of ideas for the construction and investigation of models, but it can replace neither clear formulation nor careful analysis. Fisher (1930; 1958, pp. x, 23-24, 38) not only espoused similar ideas, but he recognized also that our concepts of intuition and rigor must evolve in time. The book is neither a review of the literature nor a compendium of results. The material is almost entirely self-contained. The first eight chapters are a thoroughly revised and greatly extended version of my published lecture notes (Nagylaki, 1977a).

Human Population Genetics

Author: John H. Relethford

Publisher: John Wiley & Sons

ISBN: 111818162X

Category: Science

Page: 296

View: 8870

Introductory guide to human population genetics and microevolutionary theory Providing an introduction to mathematical population genetics, Human Population Genetics gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study. Thorough and accessible, Human Population Genetics presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain theories central to the field. By describing changes in the frequency of genetic variants from one generation to the next, this book hones in on the mathematical basis of evolutionary theory. Human Population Genetics includes: Helpful formulae for learning ease Graphs and analogies that make basic points and relate the evolutionary process to mathematical ideas Glossary terms marked in boldface within the book the first time they appear In-text citations that act as reference points for further research Exemplary case studies Topics such as Hardy-Weinberg equilibrium, inbreeding, mutation, genetic drift, natural selection, and gene flow Human Population Genetics solidifies knowledge learned in introductory biological anthropology or biology courses and makes it applicable to genetic study. NOTE: errata for the first edition can be found at the author's website:

Introduction to Population Biology

Author: Dick Neal

Publisher: Cambridge University Press

ISBN: 9780521532235

Category: Nature

Page: 393

View: 8752

How do plant and animal populations change genetically to evolve and adapt to their local environments? How do populations grow and interact with one another through competition and predation? How does behaviour influence ecology and evolution? Introduction to Population Biology covers all these areas and more. Taking a quantitative and Darwinian perspective, the basic theory of population processes is developed using mathematical models. To allow students of biology, ecology and evolution to gain a real understanding of the subject, key features include: • step-by-step instructions for spreadsheet simulations of many basic equations to explore the outcomes or predictions of models • worked examples showing how the equations are applied to biological questions • problem sets together with detailed solutions to help the reader test their understanding • real-life examples to help the reader relate the theory to the natural world

Population Genetics and Microevolutionary Theory

Author: Alan R. Templeton

Publisher: John Wiley & Sons

ISBN: 0470047216

Category: Science

Page: 720

View: 4689

The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

Population Genetics

Author: Matthew Hamilton

Publisher: John Wiley & Sons

ISBN: 1444362453

Category: Science

Page: 424

View: 830

This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.

Population Genetics

A Concise Guide

Author: John H. Gillespie

Publisher: JHU Press

ISBN: 9781421401706

Category: Science

Page: 232

View: 3992

This book is indispensable for students working in a laboratory setting or studying free-ranging populations.

Mathematical Population Genetics 1

Theoretical Introduction

Author: Warren J. Ewens

Publisher: Springer Science & Business Media

ISBN: 038721822X

Category: Science

Page: 418

View: 9082

This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.

Understanding Population Genetics

Author: Torbjörn Säll,Bengt O. Bengtsson

Publisher: John Wiley & Sons

ISBN: 1119124034

Category: Science

Page: 278

View: 9275

Interpretations, extensions and comments -- Altruism and natural selection via individuals and groups -- Frequency-dependent selection and resource competition -- Rare allele advantage due to infections and self-incompatibility -- Questions -- Chapter 9 Selection on a quantitative trait -- Analysis -- Selection in quantitative genetics -- Selection in population genetics - one more time -- Notations and assumptions -- Combining the tools -- Summing up -- Interpretations, extensions and comments -- The genetic effect of selection on a quantitative trait -- The limits of selection and the nature of -- Threshold selection and disease liability -- Quantitative genetics is not suited for causal analyses -- Chapter 10 Evolutionary genetic analysis of the sex ratio -- Analysis -- Assumptions and notations -- Finding the recursion equation system -- Testing for stability -- Summing up -- Interpretations, extensions and comments -- Sex ratio selection -- An explanation of well-delimited validity -- Meiotic recombination is an evolved genetic system -- Evolutionary genetic analysis -- What's next? -- Estimates and tests in population genetics -- The mutation-selection balance -- Partial genetic isolation -- Segregation distortion and genetic conflicts -- Epilogue -- Thanks -- Glossary -- Answers -- References -- Index -- EULA

Conservation and the Genetics of Populations

Author: Fred W. Allendorf,Gordon H. Luikart,Sally N. Aitken

Publisher: John Wiley & Sons

ISBN: 1118408578

Category: Science

Page: 632

View: 2938

Loss of biodiversity is among the greatest problems facing the world today. Conservation and the Genetics of Populations gives a comprehensive overview of the essential background, concepts, and tools needed to understand how genetic information can be used to conserve species threatened with extinction, and to manage species of ecological or commercial importance. New molecular techniques, statistical methods, and computer programs, genetic principles, and methods are becoming increasingly useful in the conservation of biological diversity. Using a balance of data and theory, coupled with basic and applied research examples, this book examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, the interpretation of genetic data from natural populations, and how these can be applied to conservation. The book includes examples from plants, animals, and microbes in wild and captive populations. This second edition contains new chapters on Climate Change and Exploited Populations as well as new sections on genomics, genetic monitoring, emerging diseases, metagenomics, and more. One-third of the references in this edition were published after the first edition. Each of the 22 chapters and the statistical appendix have a Guest Box written by an expert in that particular topic (including James Crow, Louis Bernatchez, Loren Rieseberg, Rick Shine, and Lisette Waits). This book is essential for advanced undergraduate and graduate students of conservation genetics, natural resource management, and conservation biology, as well as professional conservation biologists working for wildlife and habitat management agencies. Additional resources for this book can be found at:

Elements of Evolutionary Genetics

Author: Brian Charlesworth

Publisher: Roberts Publishers


Category: Science

Page: 734

View: 2301

Evolutionary genetics considers the causes of evolutionary change and the nature of variability in evolution. The methods of evolutionary genetics are critically important for the analysis and interpretation of the massive datasets on DNA sequence variation and evolution that are becoming available, as well for our understanding of evolution in general. This book shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data. The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure. The final two chapters demonstrate how the theory illuminates our understanding of the evolution of breeding systems, sex ratios and life histories, and some aspects of genome evolution.

Theory of Population Genetics and Evolutionary Ecology

An Introduction

Author: Jonathan Roughgarden,Joan Roughgarden

Publisher: Benjamin-Cummings Publishing Company

ISBN: 9780134419657

Category: Medical

Page: 612

View: 1116

This is a reprint of a classic which synthesizes population, genetics, and population genetics to form one of the first books on evolutionary ecology. Written by one of the foremost authorities in the field, it is designed as an introduction useful to readers at various levels from diverse backgrounds. It features balanced, readable coverge of both elementary and advanced topics that are essential to those interested in evolutionary biology, ecology, animal behavior, sociobiology, and paleobiology.

Coalescent Theory

An Introduction

Author: John Wakeley

Publisher: Roberts Publishers

ISBN: 9780974707754

Category: Medical

Page: 326

View: 6029

"An introduction to coalescent theory, which provides the foundation for molecular population genetics and genomics. Coalescent theory is the conceptual framework for studies of DNA sequence variation within species, and is the source of essential tools for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data"--Provided by publisher.

Principles of Population Genetics

Author: Daniel L. Hartl,Andrew G. Clark

Publisher: Sinauer Associates Incorporated

ISBN: 9780878933082

Category: Science

Page: 652

View: 2462

This edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level.

Introduction to Forest Genetics

Author: Jonathan Wright

Publisher: Elsevier

ISBN: 0323148883

Category: Gardening

Page: 480

View: 4338

Introduction to Forest Genetics examines some of the basic genetic concepts typically used in forestry and tree improvement studies, including Mendelian and population genetics. It also describes techniques that are generally useful in tree improvement work, including individual tree selection and breeding, provenance testing, species and racial hybridization, and introduction of exotics. Organized into 19 chapters, this volume begins with an overview of forest genetics and problems associated with forest genetics. It then discusses concepts from basic genetics, including chromosome structure and function; DNA and RNA; nongenetic inheritance; and genotype versus phenotype. Other chapters focus on inbreeding: complete elimination of homozygous recessive trees; mutation and migration; and controlled pollination and vegetative propagation. The book also covers the establishment and measurement of test plantations; general principles and methods of selective breeding; choice of breeding method and type of seed orchard; heritability and genetic gain; geographic variation in Scotch pine and American trees; species and racial hybridization; chromosome studies; and polyploidy and haploidy breeding. This book is a valuable resource for foresters, professional tree breeders, and those with or without previous training in genetics or forestry.