From Genes to Genomes
Author: Leland Hartwell
Publisher: McGraw-Hill Higher Education
Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The 5th edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed.
Author: Leland Hartwell,Leroy Hood,Charles (Chip) Aquadro,Michael L. Goldberg,Maria Papaconstantinou,Fischer, Janice,Jim Karagiannis
Publisher: McGraw-Hill Ryerson
The 2nd Canadian edition of Genetics: From Genes to Genomes emphasizes not only the core concepts of genetics, but also the cutting-edge discoveries, modern tools, and analytical methods that have made the science of genetics the exciting, vibrant, and dynamic discipline that it is today. This edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the new molecular discoveries that have changed the way the field of genetics is viewed. Genetics: From Genes to Genomes, 2nd Canadian Edition, takes an integrated approach in its presentation of genetics, thereby giving students a strong command of genetics as practiced today by academic and corporate researchers. Principles are related throughout the text in examples, essays, case histories, and Connections sections to make sure students fully understand the relationships between topics. McGraw-Hill Connect� is an award-winning digital teaching and learning platform that helps students get better results, learn and study more efficiently; while helping instructors to increase student engagement, save time with course management, and improve overall course retention. Connect includes SmartBook�, the first and only adaptive reading experience that changes reading from a passive and linear experience, to an engaging and dynamic one. Students' retain more concepts and come to class better prepared. Connect access is available for students to purchase separately, or available to package with the print text.
From Genes to Genomes
Author: Leland Hartwell
"Genetics: From Genes to Genomes" is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The Third Edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the new molecular discoveries that have changed the way the field of genetics is viewed.
Author: Michael Goldberg,Ruth Veres,Leland Hartwell,Ann E. Reynolds,Lee Silver,Leroy Hood
Publisher: McGraw-Hill Education
Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The 5th edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed. Users who purchase Connect Plus receive access to the full online ebook version of the textbook as well as SmartBook.
Author: Tom Strachan,Andrew Read
Publisher: Garland Science
Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics. While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject. The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.
Concepts and Applications of DNA Technology
Author: Jeremy W. Dale,Malcolm von Schantz,Nicholas Plant
Publisher: John Wiley & Sons
The latest edition of this highly successful textbook introduces the key techniques and concepts involved in cloning genes and in studying their expression and variation. The new edition features: Increased coverage of whole-genome sequencing technologies and enhanced treatment of bioinformatics. Clear, two-colour diagrams throughout. A dedicated website including all figures. Noted for its outstanding balance between clarity of coverage and level of detail, this book provides an excellent introduction to the fast moving world of molecular genetics.
Genes, Genomes, and Evolution
Author: Philip Meneely,Rachel Dawes Hoang,Katherine Heston,Iruka N. Okeke
Publisher: Oxford University Press
Recent advances that allow scientists to quickly and accurately sequence a genome have revolutionized our view of the structure and function of genes as well as our understanding of evolution. A new era of genetics is underway, one that allows us to fully embrace Dobzhansky's famous statement that "Nothing in biology makes sense except in the light of evolution". Genetics: Genes, Genomes, and Evolution presents the fundamental principles of genetics and molecular biology from an evolutionary perspective as informed by genome analysis. By using what has been learned from the analyses of bacterial and eukaryotic genomes as its basis, the book unites evolution, genomics, and genetics in one narrative approach. Genomic analysis is inherently both molecular and evolutionary, and every chapter is approached from this unified perspective. Similarly, genomic studies have provided a deeper appreciation of the profound relationships between all organisms - something reflected in the book's integrated discussion of bacterial and eukaryotic evolution, genetics and genomics. It is an approach that provides students with a uniquely flexible and contemporary view of genetics, genomics, and evolution. Online Resource Centre: - Video tutorials: a series of videos that provide deeper, step-by-step explanations of a range of topics featured in the text. - Flashcards: electronic flashcards covering the key terms from the text. For registered adopters of the text: - Digital image library: Includes electronic files in PowerPoint format of every illustration, photo, graph and table from the text - Lecture notes: Editable lecture notes in PowerPoint format for each chapter help make preparing lectures faster and easier than ever. Each chapter's presentation includes a succinct outline of key concepts, and incorporates the graphics from the chapter - Library of exam-style questions: a suite of questions from which you can pick potential assignments and exams. - Test bank of multiple-choice questions: a ready-made electronic testing resource that can be customized by lecturers and delivered via their institution's virtual learning environment. - Solutions to all questions featured in the book: solutions written by the authors help make the grading of homework assignments easier. - Journal Clubs: a series of questions that guide your students through the reading and interpretation of a research paper that relates to the subject matter of a given chapter. Each Journal club includes model answers for lecturers. - Instructor's guide: The instructor's guide discusses the educational approach taken by Genetics: Genes, Genomes, and Evolution in more detail, why this approach has been taken, what benefits it offers, and how it can be adopted in your class.
Author: Mark Ptashne,Alexander Gann
Publisher: CSHL Press
Genes & Signals analyzes gene regulation from a new perspective. The first chapter describes mechanisms found in bacteria, and two subsequent chapters discuss which of these is most highly exploited in higher organisms. A final chapter relates these molecular strategies to other enzymatic processes, including those involving kinases, RNA splicing enzymes, proteases, and others. A general theme emerges, one that proposes how a rather restricted set of signals and enzymatic functions has been used in evolution to generate complex life forms of different types.
Author: Richard J. Reece
Publisher: Halsted Press
Analysis of GenesA and Genomes is a clear introduction to the theoretical and practical basis of genetic engineering, gene cloning and molecular biology. All aspects of genetic engineering in the post-genomic era are covered, beginning with the basics of DNA structure and DNA metabolism. Using an example-driven approach, the fundamentals of creating mutations in DNA, cloning in bacteria, yeast, plants and animals are all clearly presented. Newer technologies such as DNA macro and macroarrays, proteomics and bioinformatics are introduced in later chapters helping students to analyse and understand the vast amounts of data that are now available through genome sequence and function projects. Aimed at students with a basic knowledge of the molecular side of biology, this will be invaluable to those looking to better understand the complexities and capabilities of these important new technologies. A modern post-genome era introduction to key techniques used in genetic engineering. An example driven past-to-present approach to allow the experiments of today to be placed in an historical context Beautifully illustrated in full colour throughout. Associated website including updates, additional content and illustrations
Author: T. A. Brown
The previous edition of Gene Cloning, has become known world-wide as the standard introductory text to this important and exciting subject. Now, the current importance of non-cloning approaches, notably PCR, in gene cloning has led to the creation of this fourth edition which explores DNA analysis. Retaining the philosophy of the previous editions, Gene Cloning and DNA Analysis assumes the reader has little prior knowledge of the subject and clearly explains its importance, the principles of the techniques used and their applications. It is carefully laid out, with over 250 two-colour illustrations. In addition to some organisational changes within the re-written text, the fourth edition has two new chapters. The first covers the methods used to sequence genomes and how to understand a sequence after it has been obtained. The second looks in detail at the applications of gene cloning and DNA analysis in forensic science; providing an excellent illustration of the applications of DNA analysis in the real world. In Gene Cloning and DNA Analysis Terry Brown has once again provided a resource of exceptional clarity, an essential introductory text to a wide range of biological sciences students, including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. Also, as well as being required reading for many course modules, it is a perfect introductory text for any professional who needs to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied or taught should have multiple copies of the book available on their shelves. Terry Brown is Professor of Biomolecular Archaeology at the Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, Manchester, UK. Visit the companion website for more details about the book: http://www.blackwellpublishing.com/genecloning/ Fourth edition of internationally popular undergraduate text. Terry Brown is world famous for his work and writing in the area of genomes, genetics and gene cloning. Fully updated and revised. Two-colour text including approximately 250 two-colour line illustrations. New dedicated web pages for the book, including student questions, illustrations and supplementary material.
Author: Jeremy W. Dale,Simon F. Park
Publisher: John Wiley & Sons
The fifth edition of this highly successful book provides students with an essential introduction to the molecular genetics of bacteria covering the basic concepts and the latest developments. It is comprehensive, easy to use and well structured with clear two-colour diagrams throughout. Specific changes to the new edition include: More detail on sigma factors, anti-sigma factors and anti-anti sigma factors, and the difference in the frequency of sigma factors in bacteria Expand material on integrons as these are becoming increasingly important in antibiotic resistance Enhanced treatment of molecular phylogeny Complete revision and updating of the final chapter on ‘Gene Mapping and Genomics’ Two-colour illustrations throughout. The focus of the book remains firmly on bacteria and will be invaluable to students studying microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences.
Publisher: Jones & Bartlett Learning
Genetics: Analysis of Genes and Genomes continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provides students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation.
Author: Tom Strachan,Judith Goodship,Patrick Chinnery
Publisher: Taylor & Francis
Genetics and Genomics in Medicine is a new textbook written for undergraduate students, graduate students, and medical researchers that explains the science behind the uses of genetics and genomics in medicine today. Rather than focusing narrowly on rare inherited and chromosomal disorders, it is a comprehensive and integrated account of how genetics and genomics affect the whole spectrum of human health and disease. DNA technologies are explained, with emphasis on the modern techniques that have revolutionized the use of genetic information in medicine and are indicating the role of genetics in common diseases. Epigenetics and non-coding RNA are covered in-depth as are genetic approaches to treatment and prevention, including pharmacogenomics, genetic testing, and personalized medicine. Cancers are essentially genetic diseases and are given a dedicated chapter that includes new insights into its molecular basis and approaches to its detection gained from cancer genomics. Specific topics, including multiple examples of clinical disorders, molecular mechanisms, and technological advances, are profiled in boxes throughout the text.
Author: Alan J. Cann
Publisher: Academic Press
Principles of Molecular Virology, Sixth Edition, provides an easily accessible introduction to modern virology, presenting principles in a clear and concise manner. This fully updated edition explores and explains the fundamental aspects of virology, including the structure of virus particles and genome, replication, gene expression, infection, pathogenesis and subviral agents. In addition, this update reflects advances made in the field, including HIV pathogenesis, cryoelectron microscopy, bioinformatics, and RNA interference. Provides a conceptual approach to the principles of molecular virology, with important examples of new advances in virology Includes online resources for students and instructors New concepts in this edition include coverage of newly discovered and emergent viruses such as MERS and Ebola Presents new and updated information on bioinformatics and metagenomics Contains updated learning outcomes and further reading for each chapter
Author: Bruce Alberts
Publisher: Garland Science
As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.
Author: Mike Service
Publisher: Cambridge University Press
Despite numerous scientific investigations on vector-borne human infections such as malaria, Lyme disease and typhus these diseases continue to threaten human health. Understanding the role of vectors in disease transmission, and the most appropriate control strategies, is therefore essential. This book provides information on the recognition, biology, ecology and medical importance of the arthropods that affect human health. The fifth edition of this popular textbook is completely updated and incorporates the latest strategies for controlling insects, ticks and mites. Numerous illustrations, with new colour photographs of some of the most important vectors, aid recognition. A glossary of entomological and epidemiological terms is included, along with a list of commonly used insecticides and their trade names. Clearly presented in a concise style, this text is aimed at students of medical entomology, tropical medicine, parasitology and pest control. It is also essential reading for physicians, health officials and community health workers.
Author: John Sandford-Smith
Eye Diseases in Hot Climates, Second Edition covers common eye diseases, particularly those that cause blindness and can be treated or prevented. The book starts by describing the basic anatomy and physiology of the eye. The text then discusses clinical methods of eye examination, with focus on prevention; the principles of treatment; disorders of the eyelids and the lacrimal apparatus; and the diseases of the conjunctiva and the psychological causes and diagnosis of conjunctivitis. The symptoms, classification, epidemiology, diagnosis, and treatment and prevention of trachoma are also discussed. The book tackles patterns of corneal disease; the signs, symptoms, epidemiology, and prevention/treatment of vitamin A deficiency in the eye; and diseases of the uvea, lens, retina, optic nerve and visual pathways. The diagnosis and treatment of glaucoma, onchocerciasis and loiasis, leprosy of the eye, squint, orbital diseases, and eye injuries, as well as the diagnosis of common eye conditions are also described. The book will be useful to ophthalmic specialists.
Author: Graham F. Hatfull,William R. Jacobs, Jr.
Publisher: American Society for Microbiology Press
A comprehensive collection of perspectives by experts in mycobacterial molecular biology Mycobacterium tuberculosis causes one in four avoidable deaths in the developing world and kills more adults than malaria, AIDS, and all tropical diseases combined. Tuberculosis was named a global health emergency by the World Health Organization, a distinction no other disease has received. Although the study of mycobacterial genetics has expanded dramatically, with new investigations into mycobacterial growth, replication, metabolism, physiology, drug susceptibility, and virulence, most of the problems in tuberculosis control that existed in 2000 remain today. Advances in our understanding of mycobacterial genetics have been reflected in exciting recent developments. New diagnostic approaches can identify drug resistance within a few hours, promising new drugs are progressing through the pipeline and into the clinic, and a range of newly developed vaccines are being evaluated. It is an exciting time as the fruits of 30 years of intensive genetic investigation are finally beginning to emerge. Written by leading experts in the field, Molecular Genetics of Mycobacteria, Second Edition, • Discusses key areas of current research in mycobacterial genetics • Explains the genetics of the physiology, metabolism, and drug sensitivities of M. tuberculosis • Presents genetic approaches for manipulating M. tuberculosis This book is an invaluable resource for anyone interested in the molecular genetics and molecular biology of mycobacteria.
Principles and Practice
Author: Robert R. Rich,Thomas A. Fleisher,William T. Shearer,Harry W. Schroeder Jr.,Anthony J. Frew,Cornelia M. Weyand
Publisher: Elsevier Health Sciences
Keep abreast of the latest advances in this complex field with the 5th Edition of Clinical Immunology: Principles and Practice. This substantially revised edition by Drs. Robert R. Rich, Thomas A. Fleisher, William T. Shearer, Harry W. Schroeder, Jr., Anthony J. Frew, and Cornelia M. Weyand, offers authoritative guidance from some of the most respected global leaders in immunology, helping you navigate today’s latest knowledge and evidence-based practices that result in improved patient care. This trusted resource features sweeping content updates, rewritten chapters, a highly clinical perspective, and an easy-to-use organization designed to enhance your diagnosis and management skills in daily practice. Includes new chapters on the Microbiota in Immunity and Inflammation, Immune Responses to Fungi, and Genetics and Genomics of Immune Response. Features extensive revisions to many chapters, including the Major Histocompatibility Complex, Multiple Sclerosis, Diabetes and Related Autoimmune Diseases, Biologic Modifiers of Inflammation and Tumor Immunotherapy. Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics. Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. Summarizes promising research and development anticipated over the next 5-10 years with "On the Horizon" boxes and discussion of translational research.