Author: Ernest Jawetz,Joseph L. Melnick,Edward A. Adelberg
Die Autoren haben beabsichtigt, diejenigen Gebiete der medizinischen Mikrobiologie kurz, exakt und in ihrem gegenwärtigen Stand darzustellen, die für die Infektionskrankheiten und ihre Chemotherapie von besonderer Bedeutung sind. Das Buch wendet sich in erster Linie an Medizinstudenten, außerdem an alle Ärzte in Krankenhaus und Praxis. Die Notwendigkeit für ein klares Verständnis der mlkrobiologischen Grundtatsachen ist in den letzten Jahren stärker geworden, da in Biochemie, Virologie und Chemotherapie so wie auf weiteren, die Medizin beeinflussenden Gebieten bedeutende Entwicklungen statt gefunden haben. Ein wesendicher Teil dieses Lehrbuches ist deswegen der Darstellung der Grundlagen gewidmet, wodurch sich das Buch auch für die Einführung des Studenten in den mikrobiologischen Kurs als brauchbar erweisen wird. Für die neue Auflage wurde ein Kapitel über Virus und Krebs neu geschrieben, und das Kapitel über antimikrobielle Chemotherapie wurde von Grund auf neu bearbeitet. Die Autoren freuen sich, bei dem Erscheinen der 7. amerikanischen Ausgabe von einer spanischen, deutschen, italienischen und griechischen Ausgabe, sowie von der Vorbereitung für eine serbokroatische Übersetzung berichten zu können. Die Autoren möchten nochmals allen danken, die ihnen bei der Bearbeitung dieser Auf lage behilflich waren, und die es ihnen durch ihre Kommentare und ihre Kritik ermöglicht haben, die in 2jährigen Abständen erscheinenden Revisionen dieses Buches auf dem neu esten Stand zu halten. ERNEsr JAWETZ JOSEPH L MELNICK San Frandsco, August 1966 EnWARD A AnELBERG III Inhaltsverzeichnis 1 Kapitell Die ~lt der Mikroben 8 Kapitel 2 Cytologie der Bakterien Optische Methoden 8 9 Eukaryote Zellstrukturen Prokaryote Zellstrukturen . 12 14 Cytoplasmatische Strukturen. 27 Färbeverfahren .
Wie die Spanische Grippe die Gesellschaft veränderte
Author: Laura Spinney
Publisher: Carl Hanser Verlag GmbH Co KG
Der Erste Weltkrieg geht zu Ende, und eine weitere Katastrophe fordert viele Millionen Tote: die Spanische Grippe. Binnen weniger Wochen erkrankt ein Drittel der Weltbevölkerung. Trotzdem sind die Auswirkungen auf Gesellschaft, Politik und Kultur weitgehend unbekannt. Ob in Europa, Asien oder Afrika, an vielen Orten brachte die Grippe die Machtverhältnisse ins Wanken, womöglich beeinflusste sie die Verhandlung des Versailler Vertrags und verursachte Modernisierungsbewegungen. Anhand von Schicksalen auf der ganzen Welt öffnet Laura Spinney das Panorama dieser Epoche. Sie füllt eine klaffende Lücke in der Geschichtsschreibung und erlaubt einen völlig neuen Blick auf das Schicksalsjahr 1918.
Anyone pursuing a career in the medical laboratory will want to have this comprehensive, yet straightforward, text. Essentials of Immunology and Serology doesn't just study the components of the immune system, it covers the way in which these components combine to generate the immune response and how these responses relate to infectious diseases, autoimmunity, tumors, hypersensitivity and transplantation. Covers the application and interpretation of a wide array of medical test kits, unlike other texts that focus only on one outdated procedure. An ideal resource for users pursuing medical lab careers that meets the immunology guidelines of the American Society of Clinical Pathologists. Key Words: immonology, serology, laboratory, immune system, autoimmunity, clinical pathology,
These proceedings contain selected contributions from the participants to the Fourth International Symposium on Dendritic cells that was held in Venice (Lido) Italy, from Oc tober 5 to 10, 1996. The symposium was attended by more than 500 scientists coming from 24 different countries. Studies on dendritic cells (DC) have been greatly hampered by the difficulties in preparing sufficient cell numbers and in a reasonable pure form. At this meeting it has been shown that large quantities of DC can be generated from precursors in both mice and humans, and this possibility has enormously encouraged studies aimed to characterize DC physiology and DC-specific genes, and to employ DC therapeutically as adjuvants for im munization. The possibility of generating large numbers of autologous DC that can be used in the manipulation of the immune response against cancer and infectious diseases has tremendously boosted dendritic cell research and the role of DC in a number of medi cal areas has been heatedly discussed.
Fundamental Immunology Seventh Edition This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed. Look inside and discover... * Fully revised and updated content reflects the latest advances in the field. * Current insights enhance readers' understanding of immune system function * Unique approach bridges the gap between basic immunology and the disease process. * Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. * Abundant illustrations and tables deliver essential information at a glance. PLUS... A convenient companion website features the fully searchable text with all references linked to PubMed. Pick up your copy today!
Grundlagen, Methoden und klinische Anwendungen der Durchflusszytometrie ; 163 Tabellen
Author: Ulrich Sack,A. Tarnok,G. Rothe
Publisher: Karger Medical and Scientific Publishers
Das vorliegende Buch ist die einzige umfassende, deutschsprachige Darstellung der Durchflusszytometrie und ihrer Anwendungen. Während einige Techniken der Immunphänotypisierung mit der Durchflusszytometrie bereits zu Routineverfahren in der Laboratoriumsmedizin geworden sind, beginnen sich neue Methoden der funktionellen Charakterisierung von Zellen, der Analyse seltener Zellen und der Diagnostik aus komplexen Materialien erst zu etablieren. Durch neue Ansätze wie die objektträgergebundene Zytometrie wird der Einsatz dieser Verfahren weiter zunehmen. Multiparameteranalysen und Miniaturisierung sind weitere Schritte zur Verbesserung der Analytik. Das Buch bietet eine umfassende, fundierte und detaillierte Zusammenstellung aller Aspekte der Durchflusszytometrie in Forschung und Klinik. Neueinsteigern gibt es eine fundierte Einführung, fortgeschrittenen Anwendern spezielle Protokolle und Interpretationshilfen.
This practical laboratory manual provides an essential source of reference, information and guidance for all laboratory and clinical immunologists. It fully describes the methods used in diagnostic immunopathology, and discusses the interpretation and value of the parameters measured. It also answers important practical questions: which parameters are useful in arriving at a diagnosis; which are useful for monitoring the severity of a disease; what level of precision is achievable, and what level is useful; how do we measure accuracy, and how do we achieve inter-laboratory consistency? Each chapter has a brief introduction which provides some general comments on the procedures involved. The methods section contains detailed descriptions with helpful notes on the advantages and disadvantages of different methods and potential pitfalls. Finally, each chapter concludes with a section on clinical applications, which discusses the interpretation, value and limitations of the information obtained, and asks what alternative interpretations should be considered, and what additional information is called for.
This textbook introduces and explains basic chiropractic philosophy and history, principles, and applications in practice. In addition to covering chiropractic care techniques, it also discusses anatomy, biomechanics, and physiology, as well as spinal analysis and diagnostic procedures. Key scientific and philosophical issues within the chiropractic community are addressed. Clearly presented material in an easy-to-follow format defines unfamiliar terms, explains and illustrates concepts, and reinforces ideas through review and critical thinking questions. The book's broad scope and discussions of diverse topics make it ideal for students or anyone in the chiropractic community. Topics and content parallel the test plan outlines from the National Board of Chiropractic Examiners, ensuring that all material is relevant, up-to-date, and accurate. Well-known chapter contributors - some of the most respected and influential names in the field - give the book a balanced approach, reflecting the diversity within the profession on issues related to the science and philosophy of chiropractic. Well-referenced discussions include the most up-to-date research. Key terms and critical thinking/review questions in each chapter familiarize the reader with important concepts and promote a solid understanding of the material.
These Proceedings contain the contributions of the partIcIpants of the Third International Symposium on Dendritic Cells that was held in Annecy, France, from June 19 to June 24, 1994. This symposium represented a follow-up of the first and second international symposia that were held in Japan in 1990 and in the Netherlands in 1992. Dendritic cells are antigen-presenting cells, and are found in all tissues and organs of the body. They can be classified into: (1) interstitial dendritic cells of the heart, kidney, gut, and lung;(2) Langerhans cells in the skin and mucous membranes; (3) interdigitating dendritic cells in the thymic medulla and secondary lymphoid tissue; and (4) blood dendritic cells and lymph dendritic cells (veiled cells). Although dendritic cells in each of these compartments are all CD45+ leukocytes that arise from the bone marrow, they may exhibit differences that relate to maturation state and microenvironment. Dendritic cells are specialized antigen-presenting cells for T lymphocytes: they process and present antigens efficiently in situ, and stimulate responses from naive and memory T cells in the paracortical area of secondary lymphoid organs. Recent evidence also demonstrates their role in induction of tolerance. By contrast, the primary and secondary B-cell follicles contain follicular dendritic cells that trap and retain intact antigen as immune complexes for long periods of time. The origin of follicular dendritic cells is not clear, but most investigators believe that these cells are not leukocytes.
Focusing on emerging therapies and those best supported by clinical trials and scientific evidence, Fundamentals of Complementary and Alternative Medicine describes some of the most prevalent and the fastest-growing CAM therapies in use today. Prominent author Dr. Marc Micozzi provides a complete overview of CAM, creating a solid foundation and context for therapies in current practice. Coverage of systems and therapies includes mind, body, and spirit; traditional Western healing; and traditional ethnomedical systems from around the world. Discussions include homeopathy, massage and manual therapies, chiropractic, a revised chapter on osteopathy, herbal medicine, aromatherapy, naturopathic medicine, and nutrition and hydration. With its wide range of topics, this is the ideal CAM reference for both students and practitioners! An evidence-based approach focuses on treatments best supported by clinical trials and scientific evidence. Coverage of CAM therapies and systems includes those most commonly encountered or growing in popularity, so you carefully evaluate each treatment. Global coverage includes discussions of traditional healing arts from Europe, Asia, Africa, and the Americas. Longevity in the market makes this a classic, trusted text. Expert contributors include well-known writers such as Kevin Ergil, Patch Adams, Joseph Pizzorno, Victor Sierpina, and Marc Micozzi himself. Suggested readings and references in each chapter list the best resources for further research and study. New, expanded organization covers the foundations of CAM, traditional Western healing, and traditional ethnomedical systems from Asia, Africa, and the Americas, putting CAM in perspective and making it easier to understand CAM origins and contexts. NEW content includes legal and operational issues in integrative medicine, creative and expressive arts therapies, ecological pharmacology, hydration, mind-body thought and practice in America, osteopathy, reflexology, South American healing, traditional medicines of India, and Unani medicine. Revised and updated chapters include aromatherapy, classical acupuncture, energy medicine, biophysical devices (electricity, light, and magnetism), massage and touch therapies, traditional osteopathy, reflexology, vitalism, and yoga. New research studies explain how and why CAM therapies work, and also demonstrate that they do work, in areas such as acupuncture, energy healing, and mind-body therapies. Expanded content on basic sciences includes biophysics, ecology, ethnomedicine, neurobiology, and pschoneuroimmunology, providing the scientific background needed to learn and practice CAM and integrative medicine. Expanded coverage of nutrition and hydration includes practical information on Vitamin D and healthy hydration with fluid and electrolytes.
The 12th edition of Guyton and Hall Textbook of Medical Physiology continues this bestselling title's long tradition as one of the world's favorite physiology textbooks. The immense success of this book is due to its description of complex physiologic principles in language that is easy to read and understand. Now with an improved color art program, thorough updates reflecting today's medicine and science, this textbook is an excellent source for mastering essential human physiology knowledge. Learn and remember vital concepts easily thanks to short, easy-to-read, masterfully edited chapters and a user-friendly full-color design. See core concepts applied to real-life situations with clinical vignettes throughout the text. Discover the newest in physiology with updates that reflect the latest advances in molecular biology, cardiovascular, neurophysiology and gastrointestinal topics. Visualize physiologic principles clearly with over 1000 bold, full-color drawings and diagrams. Distinguish core concepts from more in-depth material with a layout that uses gray shading to clearly differentiate between "need-to-know" and "nice-to-know" information.
Save hours of study time, build test taking confidence, and ace the USMLE Step 1 and course exams with most user-friendly, complete, and frequently updated review of medical microbiology and immunology available There's no faster or more effective way to prepare for the USMLE Step 1 and course exams than Medical Microbiology & Immunology Examination. Completely updated throughout, the Ninth Edition offers a concise, high-yield review of the basic and clinical aspects of bacteriology, virology, mycology, parasitology, and immunology, with an emphasis on the clinical application of microbiology and immunology to infectious diseases. Everything you need for fast and thorough exam preparation: The most frequently updated microbiology review available 600+ USMLE-format questions A complete USMLE-style exam with case-based questions Review questions and case studies to reinforce essential material An emphasis on must-know areas of bacteriology, virology, mycology, parasitology, and immunology An intense focus on clinical application Summaries of important microorganisms for rapid review Summary tables that emphasize important epidemiological aspects of infectious diseases Basic science pearls that summarize fundamental concepts Informative tables and figures An understanding of the clinical relevance of microbiology Revised and expanded coverage of HIV, hepatitis viruses and immunology
Updated and easy-to-use, Linne & Ringsrud's Clinical Laboratory Science: The Basics and Routine Techniques, 6th Edition delivers a fundamental overview of the laboratory skills and techniques essential for success in your classes and your career. Author Mary Louise Turgeon's simple, straightforward writing clarifies complex concepts, and a discipline-by-discipline approach helps you build the knowledge to confidently perform clinical laboratory tests and ensure accurate, effective results. Expert insight from respected educator and author Mary Louise Turgeon reflects the full spectrum of clinical laboratory science. Engaging full-color design and illustrations familiarize you with what you'll see under the microscope. Streamlined approach makes must-know concepts and practices more accessible. Broad scope provides an ideal introduction to clinical laboratory science at various levels, including MLS/MLT and Medical Assisting. Hands-on procedures guide you through the exact steps you'll perform in the lab. Learning objectives help you identify key chapter content and study more effectively. Case studies challenge you to apply concepts to realistic scenarios. Review questions at the end of each chapter help you assess your understanding and identify areas requiring additional study. A companion Evolve website provides convenient online access to procedures, glossary, audio glossary and links to additional information. Updated instrumentation coverage familiarizes you with the latest technological advancements in clinical laboratory science. Perforated pages make it easy for you to take procedure instructions with you into the lab. Enhanced organization helps you study more efficiently and quickly locate the information you need. Convenient glossary provides fast, easy access to definitions of key terms.
Clinical Application of Neuromuscular Techniques, Volume 2 - The Lower Body discusses the theory and practice of the manual treatment of chronic pain, especially with regards to the soft tissues of the lower body. Authored by experts of international renown, this highly successful book provides a structural review of each region, including ligaments and functional anatomy, and includes step-by-step protocols that address each muscle of a region. The volume now comes with an EVOLVE site for instructors who can download the full text and images for teaching purposes. Provides a comprehensive ‘one-stop’ volume on the treatment of somatic pain and dysfunction Designed and written to meet the needs of those working with neuromuscular dysfunction in a variety of professions All muscles covered from the perspective of assessment and treatment of myofascial pain Describes normal anatomy and physiology as well as the associated dysfunction Gives indications for treatments and guidance on making the appropriate treatment choice for each patient Combines NMT, MET, PR and much more to give a variety of treatment options for each case Describes the different NMT techniques in relation to the joint anatomy involved Practical step-by-step descriptions provided to make usage easy Includes acupuncture, hydrotherapies and nutritional support as well as guidance for the patient in the use of self-help approaches Contains up-to-date evidence based content Presents the latest research findings underpinning the practice of NMT methodology from differing areas of practice Presents the increasingly refined ways of using the variety of MET methods to allow the reader to safely apply them in a variety of settings