Other unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals alike."--BOOK JACKET.
This book is a short introduction to the engineering principles of harnessing the vast potential of microorganisms, and animal and plant cells in making biochemical products. It was written for scientists who have no background in engineering, and for engineers with minimal background in biology. The overall subject dealt with is process. But the coverage goes beyond the process of biomanufacturing in the bioreactor, and extends to the factory of cell’s biosynthetic machinery. Starting with an overview of biotechnology and organism, engineers are eased into biochemical reactions and life scientists are exposed to the technology of production using cells. Subsequent chapters allow engineers to be acquainted with biochemical pathways, while life scientist learn about stoichiometric and kinetic principles of reactions and cell growth. This leads to the coverage of reactors, oxygen transfer and scale up. Following three chapters on biomanufacturing of current and future importance, i.e. cell culture, stem cells and synthetic biology, the topic switches to product purification, first with a conceptual coverage of operations used in bioseparation, and then a more detailed analysis to provide a conceptual understanding of chromatography, the modern workhorse of bioseparation. Drawing on principles from engineering and life sciences, this book is for practitioners in biotechnology and bioengineering. The author has used the book for a course for advanced students in both engineering and life sciences. To this end, problems are provided at the end of each chapter.
This systematically organized and well-balanced book compresses within the covers of a single volume the theoretical principles and techniques involved in bio-separations, also called downstream processing. These techniques are derived from a range of subjects, for example, physical chemistry, analytical chemistry, bio-chemistry, biological science and chemical engineering. Organized in its 15 chapters, the text covers in the first few chapters topics related to chemical engineering unit operations such as filtration, centrifugation, adsorption, extraction and membrane separation as applied to bioseparations. The use of chromatography as practiced at laboratory as well as industrial scale operation and related techniques such as gel filtration, affinity and pseudoaffinity chromatography, ion-exchange chromatography, electrophoresis and related methods have been discussed. The important applications of these techniques have also been highlighted.
Technological, Educational, Business, Political Aspects
Author: C. Ronneau,O. Bitchaeva
Publisher: Springer Science & Business Media
Biotechnology for Waste Management and Site Restoration covers: waste management - solid, gaseous, liquid; site restoration - radioactivity, organics, toxic metals; educational, economic, social and business aspects; and international collaboration. International collaboration is growing apace and many concrete projects have been started. The body of knowledge is growing. Over the long term, it is envisaged that this international collaboration will result in a long-term scientific and technological strategy, new technologies and alternative solutions, and practical implementations of biotechnology for the nuclear and industrial sectors of the economy.
National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee on Opportunities in Biotechnology for Future Army Applications
Author: National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee on Opportunities in Biotechnology for Future Army Applications
Publisher: National Academies Press
This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.
Unlike extensive major reference works or handbooks, Chemical Engineering: Trends and Developments provides readers with a ready-reference to latest techniques in selected areas of chemical engineering where research is and will be focused in the future. These areas are: bioseparations; particle science and design; nanotechnology; and reaction engineering. The aim of the book is to provide academic and R&D researchers with an overview of the main areas of technical development and how these techniques can be applied. Each chapter focuses on a technique, plus a selection of applications or examples of where the technique could be applied.
Multidisciplinary resource for graduate studies and the biotechnology industry Knowledge of the genetic basis of biological functioning continues to grow at an astronomical rate, as do the challenges and opportunities of applying this information to the production of therapeutic compounds, specialty biochemicals, functional food ingredients, environmentally friendly biocatalysts, and new bioproducts from renewable resources. While genetic engineering of living organisms transforms the science of genomics into treatments for cancer, diabetes, and heart disease, or products for industry and agriculture, the science and technology of bioseparations are the keys to delivering these products in a purified form suitable for use by people. The methods, theory, and materials that reduce the science of bioseparations to practice, whether in the laboratory or the plant, are the subjects of Bioseparations Engineering. Examples address purification of biomolecules ranging from recombinant proteins to gene therapy products, with footnotes detailing economics of the products. Mechanistic analysis and engineering design methods are given for: * Isocratic and gradient chromatography * Sedimentation, centrifugation, and filtration * Membrane systems * Precipitation and crystallization Topics addressed within this framework are: stationary phase selection; separations development; modeling of ion exchange, size exclusion, reversed phase, hydrophobic interaction, and affinity chromatography; the impact of regulatory issues on chromatography process design; organization of separation strategies into logical sequences of purification steps; and bridges between molecular biology, combinatorial methods, and separations science. A result of teaching and developing the subject matter over ten years, Bioseparations Engineering is an ideal text for graduate students, as well as a timely desk book for process engineers, process scientists, researchers, and research associates in the pharmaceutical, food, and life sciences industries.
Provides information about admission, financial aid, programs and institutions, and research specialties within the fields of engineering and applied sciences, including civil engineering, information technology, and bioengineering.
This is an ideal text for an introduction to biomedical engineering. The book presents the basic science knowledge used by biomedical engineers at a level accessible to all students and illustrates the first steps in applying this knowledge to solve problems in human medicine. Biomedical engineering encompasses a range of fields of specialization including bioinstrumentation, bioimaging, biomechanics, biomaterials, and biomolecular engineering. This introduction to bioengineering assembles foundational resources from molecular and cellular biology and physiology and relates them to various sub-specialties of biomedical engineering. The first two parts of the book present basic information in molecular/cellular biology and human physiology; quantitative concepts are stressed in these sections. Comprehension of these basic life science principles provides the context in which biomedical engineers interact. The third part of the book introduces sub-specialties in biomedical engineering, and emphasizes - through examples and profiles of people in the field - the types of problems biomedical engineers solve.
Artificial Intelligence in Process Engineering aims to present a diverse sample of Artificial Intelligence (AI) applications in process engineering. The book contains contributions, selected by the editors based on educational value and diversity of AI methods and process engineering application domains. Topics discussed in the text include the use of qualitative reasoning for modeling and simulation of chemical systems; the use of qualitative models in discrete event simulation to analyze malfunctions in processing systems; and the diagnosis of faults in processes that are controlled by Programmable Logic Controllers. There are also debates on the issue of quantitative versus qualitative information. The control of batch processes, a design of a system that synthesizes bioseparation processes, and process design in the domain of chemical (rather than biochemical) systems are likewise covered in the text. This publication will be of value to industrial engineers and process engineers and researchers.
Das von renommierten Wissenschaftlern verschiedener Fachgebiete verfasste Buch fuhrt in die physikalischen, chemischen und elektronischen Grundlagen der Nanotechnologie ein und zeigt die speziellen Fertigungstechniken und Anwendungsmoglichkeiten auf. Anhange mit kurzen Darstellungen von wichtigen Messtechniken wie Elektronenmikroskopie, Sekundarionenspektroskopie, Photoemissionsspektroskopie und kernmagnetische Resonanz (NMR) vervollstandigen das Buch."