An Introduction to Population Genetics

Theory and Applications

Author: Rasmus Nielsen,Montgomery Slatkin

Publisher: Sinauer Associates Incorporated

ISBN: 9781605351537

Category: Science

Page: 287

View: 8202

"A text for a one-semester course in population genetics. It introduces students to classical population genetics (in terms of allele and haplotype frequencies) and modern population genetics (in terms of coalescent theory). It presents numerous applications of population genetic methods to practical problems, including testing for natural selection, detecting genetic hitchhiking and inferring the history of populations"--Provided by publisher.

Introduction to Population Genetics

Author: Richard Halliburton

Publisher: Benjamin-Cummings Publishing Company

ISBN: 9780130163806

Category: Science

Page: 650

View: 9369

Making the theory of population genetics relevant to readers, this book explains the related mathematics with a logical organization.It presents the quantitative aspects of population genetics, and employs examples of human genetics, medical evolution, human evolution, and endangered species.For an introduction to, and understanding of, population genetics.

An Introduction to Population Genetics Theory

Author: James F. Crow,Motoo Kimura

Publisher: N.A

ISBN: 9781932846126

Category: Mathematics

Page: 591

View: 622

Originally published in 1970, this classic in the field of population genetics opens with elementary concepts and deals primarily with natural populations and less fully with the rather similar problems that arise in breeding livestock and cultivated plants.

Human Population Genetics

Author: John H. Relethford

Publisher: John Wiley & Sons

ISBN: 111818162X

Category: Science

Page: 296

View: 2871

Introductory guide to human population genetics and microevolutionary theory Providing an introduction to mathematical population genetics, Human Population Genetics gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study. Thorough and accessible, Human Population Genetics presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain theories central to the field. By describing changes in the frequency of genetic variants from one generation to the next, this book hones in on the mathematical basis of evolutionary theory. Human Population Genetics includes: Helpful formulae for learning ease Graphs and analogies that make basic points and relate the evolutionary process to mathematical ideas Glossary terms marked in boldface within the book the first time they appear In-text citations that act as reference points for further research Exemplary case studies Topics such as Hardy-Weinberg equilibrium, inbreeding, mutation, genetic drift, natural selection, and gene flow Human Population Genetics solidifies knowledge learned in introductory biological anthropology or biology courses and makes it applicable to genetic study. NOTE: errata for the first edition can be found at the author's website: http://employees.oneonta.edu/relethjh/HPG/errata.pdf

Population Genetics

Author: Matthew Hamilton

Publisher: John Wiley & Sons

ISBN: 1444362453

Category: Science

Page: 424

View: 909

This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.

Introduction to Theoretical Population Genetics

Author: Thomas Nagylaki

Publisher: Springer Science & Business Media

ISBN: 364276214X

Category: Science

Page: 369

View: 6497

This book covers those areas of theoretical population genetics that can be investigated rigorously by elementary mathematical methods. I have tried to formulate the various models fairly generally and to state the biological as sumptions quite explicitly. I hope the choice and treatment of topics will en able the reader to understand and evaluate detailed analyses of many specific models and applications in the literature. Models in population genetics are highly idealized, often even over idealized, and their connection with observation is frequently remote. Further more, it is not practicable to measure the parameters and variables in these models with high accuracy. These regrettable circumstances amply justify the use of appropriate, lucid, and rigorous approximations in the analysis of our models, and such approximations are often illuminating even when exact solu tions are available. However, our empirical and theoretical limitations justify neither opaque, incomplete formulations nor unconvincing, inadequate analy ses, for these may produce uninterpretable, misleading, or erroneous results. Intuition is a principal source of ideas for the construction and investigation of models, but it can replace neither clear formulation nor careful analysis. Fisher (1930; 1958, pp. x, 23-24, 38) not only espoused similar ideas, but he recognized also that our concepts of intuition and rigor must evolve in time. The book is neither a review of the literature nor a compendium of results. The material is almost entirely self-contained. The first eight chapters are a thoroughly revised and greatly extended version of my published lecture notes (Nagylaki, 1977a).

An Introduction to Forensic Genetics

Author: William Goodwin,Adrian Linacre,Sibte Hadi

Publisher: John Wiley & Sons

ISBN: 0470010258

Category: Science

Page: 162

View: 8049

An Introduction to Forensic Genetics is a comprehensive introduction to this fast moving area from the collection of evidence at the scene of a crime to the presentation of that evidence in a legal context. The last few years have seen significant advances in the subject and the development and application of genetics has revolutionised forensic science. This book begins with the key concepts needed to fully appreciate the subject and moves on to examine the latest developments in the field, illustrated throughout with references to relevant casework. In addition to the technology involved in generating a DNA profile, the underlying population biology and statistical interpretation are also covered. The evaluation and presentation of DNA evidence in court is discussed as well with guidance on the evaluation process and how court reports and statements should be presented. An accessible introduction to Forensic Genetics from the collection of evidence to the presentation of that evidence in a legal context Includes case studies to enhance student understanding Includes the latest developments in the field focusing on the technology used today and that which is likely to be used in the future Accessible treatment of population biology and statistics associated with forensic evidence This book offers undergraduate students of Forensic Science an accessible approach to the subject that will have direct relevance to their courses. An Introduction to Forensic Genetics is also an invaluable resource for postgraduates and practising forensic scientists looking for a good introduction to the field.

Population Genetics and Microevolutionary Theory

Author: Alan R. Templeton

Publisher: John Wiley & Sons

ISBN: 0470047216

Category: Science

Page: 720

View: 1192

The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

An Introduction to Human Molecular Genetics

Mechanisms of Inherited Diseases

Author: Jack J. Pasternak

Publisher: John Wiley & Sons

ISBN: 047171917X

Category: Science

Page: 512

View: 971

An Introduction to Human Molecular Genetics Second Edition Jack J. Pasternak The Second Edition of this internationally acclaimed text expands its coverage of the molecular genetics of inherited human diseases with the latest research findings and discoveries. Using a unique, systems-based approach, the text offers readers a thorough explanation of the gene discovery process and how defective genes are linked to inherited disease states in major organ and tissue systems. All the latest developments in functional genomics, proteomics, and microarray technology have been thoroughly incorporated into the text. The first part of the text introduces readers to the fundamentals of cytogenetics and Mendelian genetics. Next, techniques and strategies for gene manipulation, mapping, and isolation are examined. Readers will particularly appreciate the text's exceptionally thorough and clear explanation of genetic mapping. The final part features unique coverage of the molecular genetics of distinct biological systems, covering muscle, neurological, eye, cancer, and mitochondrial disorders. Throughout the text, helpful figures and diagrams illustrate and clarify complex material. Readers familiar with the first edition will recognize the text's same lucid and engaging style, and will find a wealth of new and expanded material that brings them fully up to date with a current understanding of the field, including: * New chapters on complex genetic disorders, genomic imprinting, and human population genetics * Expanded and fully revised section on clinical genetics, covering diagnostic testing, molecular screening, and various treatments This text is targeted at upper-level undergraduate students, graduate students, and medical students. It is also an excellent reference for researchers and physicians who need a clinically relevant reference for the molecular genetics of inherited human diseases.

An Introduction to Molecular Anthropology

Author: Mark Stoneking

Publisher: John Wiley & Sons

ISBN: 1118061624

Category: Science

Page: 400

View: 2219

Filling a unique and unmet need for introductory molecular anthropology texts, An Introduction to Molecular Anthropology covers basic genetic concepts, such as what genes are, what they do, and how they are inherited. Organized into three major sections, chapters build from basic genetic and evolutionary concepts to using genetics to make inferences about culture and molecular anthropology in the genomics age. This essential primer in genetics and molecular anthropology is suitable as a supplemental resource, a stand-alone text, and an introduction and reference for professionals.

An Introduction to Molecular Ecology

Author: Graham Rowe,Michael Sweet,Trevor Beebee

Publisher: Oxford University Press

ISBN: 0198716990

Category:

Page: 400

View: 2080

An Introduction to Molecular Ecology combines theoretical concepts with practice-driven examples to showcase the latest molecular and genomic techniques and their impact on the study of ecology. The opening chapters introduce the essential molecular and genetic concepts that underpin the subject and describe key molecular tools and methods available to the ecologist. Capturing the broad scope of the field, the book goes on to explore the use of molecular tools in the context of behaviouralecology, population genetics, phylogeography, conservation, and microbial ecology. The third edition includes coverage of exciting new technological and analytical developments, such as next generation sequencing, which have revolutionized the field over the last decade. Molecular ecology is now in a position to tackle some truly ecological questions for the first time since itsinception. Blending conceptual detail with the most instructive examples, An Introduction to Molecular Ecology is an ideal resource for those new to the subject needing to develop a strong working understanding of the field. Online Resource Centre: The Online Resource Centre to accompany An Introduction to Molecular Ecology features: For students: * Suggested review articles to take your learning further * Links to useful websites and software * A range of questions to consolidate your learning and understanding For registered adopters of the book: * Journal Club; suggested research papers and discussion questions linked to topics featured in the book * Figures from the textbook to view and download

An Introduction to Genetic Algorithms

Author: Melanie Mitchell

Publisher: MIT Press

ISBN: 9780262631853

Category: Computers

Page: 209

View: 2774

Genetic algorithms are used in science and engineering for problem solving and as computational models. This brief introduction enables readers to implement and experiment with genetic algorithms on their own. The descriptions of applications and modeling projects stretch beyond the boundaries of computer science to include systems theory, game theory, biology, ecology, and population genetics. 20 illustrations.

Theory of Population Genetics and Evolutionary Ecology

An Introduction

Author: Jonathan Roughgarden,Joan Roughgarden

Publisher: Benjamin-Cummings Publishing Company

ISBN: 9780134419657

Category: Medical

Page: 612

View: 8469

This is a reprint of a classic which synthesizes population, genetics, and population genetics to form one of the first books on evolutionary ecology. Written by one of the foremost authorities in the field, it is designed as an introduction useful to readers at various levels from diverse backgrounds. It features balanced, readable coverge of both elementary and advanced topics that are essential to those interested in evolutionary biology, ecology, animal behavior, sociobiology, and paleobiology.

Understanding Population Genetics

Author: Torbjörn Säll,Bengt O. Bengtsson

Publisher: John Wiley & Sons

ISBN: 1119124034

Category: Science

Page: 278

View: 2185

Interpretations, extensions and comments -- Altruism and natural selection via individuals and groups -- Frequency-dependent selection and resource competition -- Rare allele advantage due to infections and self-incompatibility -- Questions -- Chapter 9 Selection on a quantitative trait -- Analysis -- Selection in quantitative genetics -- Selection in population genetics - one more time -- Notations and assumptions -- Combining the tools -- Summing up -- Interpretations, extensions and comments -- The genetic effect of selection on a quantitative trait -- The limits of selection and the nature of -- Threshold selection and disease liability -- Quantitative genetics is not suited for causal analyses -- Chapter 10 Evolutionary genetic analysis of the sex ratio -- Analysis -- Assumptions and notations -- Finding the recursion equation system -- Testing for stability -- Summing up -- Interpretations, extensions and comments -- Sex ratio selection -- An explanation of well-delimited validity -- Meiotic recombination is an evolved genetic system -- Evolutionary genetic analysis -- What's next? -- Estimates and tests in population genetics -- The mutation-selection balance -- Partial genetic isolation -- Segregation distortion and genetic conflicts -- Epilogue -- Thanks -- Glossary -- Answers -- References -- Index -- EULA

Population Genetics

A Concise Guide

Author: John H. Gillespie

Publisher: JHU Press

ISBN: 9781421401706

Category: Science

Page: 232

View: 4506

This book is indispensable for students working in a laboratory setting or studying free-ranging populations.

Coalescent Theory

An Introduction

Author: John Wakeley

Publisher: Roberts Publishers

ISBN: 9780974707754

Category: Medical

Page: 326

View: 1763

"An introduction to coalescent theory, which provides the foundation for molecular population genetics and genomics. Coalescent theory is the conceptual framework for studies of DNA sequence variation within species, and is the source of essential tools for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data"--Provided by publisher.

Elements of Evolutionary Genetics

Author: Brian Charlesworth

Publisher: Roberts Publishers

ISBN: N.A

Category: Science

Page: 734

View: 3163

Evolutionary genetics considers the causes of evolutionary change and the nature of variability in evolution. The methods of evolutionary genetics are critically important for the analysis and interpretation of the massive datasets on DNA sequence variation and evolution that are becoming available, as well for our understanding of evolution in general. This book shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data. The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure. The final two chapters demonstrate how the theory illuminates our understanding of the evolution of breeding systems, sex ratios and life histories, and some aspects of genome evolution.

Conservation and the Genetics of Populations

Author: Fred W. Allendorf,Gordon H. Luikart,Sally N. Aitken

Publisher: John Wiley & Sons

ISBN: 1118408578

Category: Science

Page: 632

View: 9777

Loss of biodiversity is among the greatest problems facing the world today. Conservation and the Genetics of Populations gives a comprehensive overview of the essential background, concepts, and tools needed to understand how genetic information can be used to conserve species threatened with extinction, and to manage species of ecological or commercial importance. New molecular techniques, statistical methods, and computer programs, genetic principles, and methods are becoming increasingly useful in the conservation of biological diversity. Using a balance of data and theory, coupled with basic and applied research examples, this book examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, the interpretation of genetic data from natural populations, and how these can be applied to conservation. The book includes examples from plants, animals, and microbes in wild and captive populations. This second edition contains new chapters on Climate Change and Exploited Populations as well as new sections on genomics, genetic monitoring, emerging diseases, metagenomics, and more. One-third of the references in this edition were published after the first edition. Each of the 22 chapters and the statistical appendix have a Guest Box written by an expert in that particular topic (including James Crow, Louis Bernatchez, Loren Rieseberg, Rick Shine, and Lisette Waits). This book is essential for advanced undergraduate and graduate students of conservation genetics, natural resource management, and conservation biology, as well as professional conservation biologists working for wildlife and habitat management agencies. Additional resources for this book can be found at: www.wiley.com/go/allendorf/populations.