An Introduction to Infectious Disease Modelling

Author: Emilia Vynnycky,Richard White

Publisher: Oxford University Press

ISBN: 0198565763

Category: Mathematics

Page: 370

View: 9192

Mathematical models are increasingly being used to examine questions in infectious disease control. Applications include predicting the impact of vaccination strategies against common infections and determining optimal control strategies against HIV and pandemic influenza. This book introduces individuals interested in infectious diseases to this exciting and expanding area. The mathematical level of the book is kept as simple as possible, which makes the book accessible to those who have not studied mathematics to university level. Understanding is further enhanced by models that can be accessed online, which will allow readers to explore the impact of different factors and control strategies, and further adapt and develop the models themselves. The book is based on successful courses developed by the authors at the London School of Hygiene and Tropical Medicine. It will be of interest to epidemiologists, public health researchers, policy makers, veterinary scientists, medical statisticians and infectious disease researchers.

An Introduction to Mathematical Modeling of Infectious Diseases

Author: Michael Y. Li

Publisher: Springer

ISBN: 3319721224

Category: Mathematics

Page: 156

View: 3898

This text provides essential modeling skills and methodology for the study of infectious diseases through a one-semester modeling course or directed individual studies. The book includes mathematical descriptions of epidemiological concepts, and uses classic epidemic models to introduce different mathematical methods in model analysis. Matlab codes are also included for numerical implementations. It is primarily written for upper undergraduate and beginning graduate students in mathematical sciences who have an interest in mathematical modeling of infectious diseases. Although written in a rigorous mathematical manner, the style is not unfriendly to non-mathematicians.

Modeling Infectious Diseases in Humans and Animals

Author: Matt J. Keeling,Pejman Rohani

Publisher: Princeton University Press

ISBN: 1400841038

Category: Science

Page: 408

View: 3641

For epidemiologists, evolutionary biologists, and health-care professionals, real-time and predictive modeling of infectious disease is of growing importance. This book provides a timely and comprehensive introduction to the modeling of infectious diseases in humans and animals, focusing on recent developments as well as more traditional approaches. Matt Keeling and Pejman Rohani move from modeling with simple differential equations to more recent, complex models, where spatial structure, seasonal "forcing," or stochasticity influence the dynamics, and where computer simulation needs to be used to generate theory. In each of the eight chapters, they deal with a specific modeling approach or set of techniques designed to capture a particular biological factor. They illustrate the methodology used with examples from recent research literature on human and infectious disease modeling, showing how such techniques can be used in practice. Diseases considered include BSE, foot-and-mouth, HIV, measles, rubella, smallpox, and West Nile virus, among others. Particular attention is given throughout the book to the development of practical models, useful both as predictive tools and as a means to understand fundamental epidemiological processes. To emphasize this approach, the last chapter is dedicated to modeling and understanding the control of diseases through vaccination, quarantine, or culling. Comprehensive, practical introduction to infectious disease modeling Builds from simple to complex predictive models Models and methodology fully supported by examples drawn from research literature Practical models aid students' understanding of fundamental epidemiological processes For many of the models presented, the authors provide accompanying programs written in Java, C, Fortran, and MATLAB In-depth treatment of role of modeling in understanding disease control

Mathematical Epidemiology

Author: Fred Brauer,Pauline van den Driessche,J. Wu

Publisher: Springer Science & Business Media

ISBN: 3540789103

Category: Medical

Page: 414

View: 3782

Based on lecture notes of two summer schools with a mixed audience from mathematical sciences, epidemiology and public health, this volume offers a comprehensive introduction to basic ideas and techniques in modeling infectious diseases, for the comparison of strategies to plan for an anticipated epidemic or pandemic, and to deal with a disease outbreak in real time. It covers detailed case studies for diseases including pandemic influenza, West Nile virus, and childhood diseases. Models for other diseases including Severe Acute Respiratory Syndrome, fox rabies, and sexually transmitted infections are included as applications. Its chapters are coherent and complementary independent units. In order to accustom students to look at the current literature and to experience different perspectives, no attempt has been made to achieve united writing style or unified notation. Notes on some mathematical background (calculus, matrix algebra, differential equations, and probability) have been prepared and may be downloaded at the web site of the Centre for Disease Modeling (

An Introduction to Mathematical Epidemiology

Author: Maia Martcheva

Publisher: Springer

ISBN: 1489976124

Category: Mathematics

Page: 453

View: 3574

The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of infectious diseases. It includes model building, fitting to data, local and global analysis techniques. Various types of deterministic dynamical models are considered: ordinary differential equation models, delay-differential equation models, difference equation models, age-structured PDE models and diffusion models. It includes various techniques for the computation of the basic reproduction number as well as approaches to the epidemiological interpretation of the reproduction number. MATLAB code is included to facilitate the data fitting and the simulation with age-structured models.

Infectious Disease Epidemiology

Author: Ibrahim Abubakar,Helen R. Stagg,Ted Cohen,Laura C. Rodrigues

Publisher: Oxford University Press

ISBN: 0191030546

Category: Medical

Page: 416

View: 9194

Infectious Disease Epidemiology is a concise reference guide which provides trainees and practicing epidemiologists with the information that they need to understand the basic concepts necessary for working in this specialist area. Divided into two sections, part one comprehensively covers the basic principles and methods relevant to the study of infectious disease epidemiology. It is organised in order of increasing complexity, ranging from a general introduction to subjects such as mathematical modelling and sero-epidemiology. Part two examines key major infectious diseases that are of global significance. Grouped by their route of transmission for ease of reference, they include diseases that present a particular burden or a high potential for causing mortality. This practical guide will be essential reading for postgraduate students in infectious disease epidemiology, health protection trainees, and practicing epidemiologists.

Hot Zone

Ebola, das tödliche Virus

Author: Richard Preston

Publisher: Knaur eBook

ISBN: 3426434571

Category: Health & Fitness

Page: 368

View: 3369

Richard Prestons populärwissenschaftlicher Tatsachen-Thriller liest sich spannender als jeder Horror-Roman. Preston berichtet darin über die ersten Infektionen mit dem Ebola-Virus vor über vierzig Jahren. Sein Tatsachenthriller von 1998 ist immer noch hochaktuell, wie die schreckliche Ebola-Epidemie in Zentralafrika gerade zeigt. Ebola gehört zu den gefährlichsten Killerviren. Diese aus dem Afrikanischen Regenwald stammenden sogenannten „Filoviren“, können einen Menschen auf grausamste Art und Weise töten. Das Virus löst innerhalb weniger Tage die inneren Organe auf, und der Erkrankte verblutet von innen. Das Virus ist zudem extrem ansteckend, und weltweit gibt es immer noch kein wirksames Heilmittel dagegen. Deshalb ist es nicht auszuschließen, dass die Menschheit eines Tages einer Seuche wie Ebola erliegen könnte. Preston schildert, wie der Ebola-Erreger über Affen, die für medizinische Versuche importiert wurden, schließlich nach Amerika kommt. In einem kleinen Labor in Reston, USA, verbreitet er Angst und Schrecken. Als sich die Seuche unter den im Quarantänelager zusammengepferchten Affen ausbreitet, rufen die Betreiber der Anlage die Gesundheitsbehörden zu Hilfe. Bald müssen die Wissenschaftler feststellen, dass sich das Virus inzwischen nicht nur durch Kontakt, sondern auch durch die Luft verbreiten kann.

Medizinische Mikrobiologie

Author: Ernest Jawetz,Joseph L. Melnick,Edward A. Adelberg

Publisher: Springer-Verlag

ISBN: 3662001551

Category: Science

Page: N.A

View: 9256

Die Autoren haben beabsichtigt, diejenigen Gebiete der medizinischen Mikrobiologie kurz, exakt und in ihrem gegenwärtigen Stand darzustellen, die für die Infektionskrankheiten und ihre Chemotherapie von besonderer Bedeutung sind. Das Buch wendet sich in erster Linie an Medizinstudenten, außerdem an alle Ärzte in Krankenhaus und Praxis. Die Notwendigkeit für ein klares Verständnis der mlkrobiologischen Grundtatsachen ist in den letzten Jahren stärker geworden, da in Biochemie, Virologie und Chemotherapie so wie auf weiteren, die Medizin beeinflussenden Gebieten bedeutende Entwicklungen statt gefunden haben. Ein wesendicher Teil dieses Lehrbuches ist deswegen der Darstellung der Grundlagen gewidmet, wodurch sich das Buch auch für die Einführung des Studenten in den mikrobiologischen Kurs als brauchbar erweisen wird. Für die neue Auflage wurde ein Kapitel über Virus und Krebs neu geschrieben, und das Kapitel über antimikrobielle Chemotherapie wurde von Grund auf neu bearbeitet. Die Autoren freuen sich, bei dem Erscheinen der 7. amerikanischen Ausgabe von einer spanischen, deutschen, italienischen und griechischen Ausgabe, sowie von der Vorbereitung für eine serbokroatische Übersetzung berichten zu können. Die Autoren möchten nochmals allen danken, die ihnen bei der Bearbeitung dieser Auf lage behilflich waren, und die es ihnen durch ihre Kommentare und ihre Kritik ermöglicht haben, die in 2jährigen Abständen erscheinenden Revisionen dieses Buches auf dem neu esten Stand zu halten. ERNEsr JAWETZ JOSEPH L MELNICK San Frandsco, August 1966 EnWARD A AnELBERG III Inhaltsverzeichnis 1 Kapitell Die ~lt der Mikroben 8 Kapitel 2 Cytologie der Bakterien Optische Methoden 8 9 Eukaryote Zellstrukturen Prokaryote Zellstrukturen . 12 14 Cytoplasmatische Strukturen. 27 Färbeverfahren .

Wahrscheinlichkeitsrechnung (Ars Conjectandi)

Author: Jakob Bernoulli

Publisher: Wentworth Press

ISBN: 9780270072112


Page: 170

View: 6488

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Epidemic Modelling

An Introduction

Author: D. J. Daley,J. Gani

Publisher: Cambridge University Press

ISBN: 9780521014670

Category: Mathematics

Page: 213

View: 4282

This is a general introduction to the mathematical modelling of diseases.

Mathematical Approaches for Emerging and Reemerging Infectious Diseases: Models, Methods, and Theory

Author: Carlos Castillo-Chavez,Sally Blower,Pauline van den Driessche,Denise Kirschner,Abdul-Aziz Yakubu

Publisher: Springer Science & Business Media

ISBN: 9780387953557

Category: Medical

Page: 377

View: 9331

This IMA Volume in Mathematics and its Applications MATHEMATICAL APPROACHES FOR EMERGING AND REEMERGING INFECTIOUS DISEASES: MODELS, AND THEORY METHODS is based on the proceedings of a successful one week workshop. The pro ceedings of the two-day tutorial which preceded the workshop "Introduction to Epidemiology and Immunology" appears as IMA Volume 125: Math ematical Approaches for Emerging and Reemerging Infectious Diseases: An Introduction. The tutorial and the workshop are integral parts of the September 1998 to June 1999 IMA program on "MATHEMATICS IN BI OLOGY. " I would like to thank Carlos Castillo-Chavez (Director of the Math ematical and Theoretical Biology Institute and a member of the Depart ments of Biometrics, Statistics and Theoretical and Applied Mechanics, Cornell University), Sally M. Blower (Biomathematics, UCLA School of Medicine), Pauline van den Driessche (Mathematics and Statistics, Uni versity of Victoria), and Denise Kirschner (Microbiology and Immunology, University of Michigan Medical School) for their superb roles as organizers of the meetings and editors of the proceedings. Carlos Castillo-Chavez, es pecially, made a major contribution by spearheading the editing process. I am also grateful to Kenneth L. Cooke (Mathematics, Pomona College), for being one of the workshop organizers and to Abdul-Aziz Yakubu (Mathe matics, Howard University) for serving as co-editor of the proceedings. I thank Simon A. Levin (Ecology and Evolutionary Biology, Princeton Uni versity) for providing an introduction.

Modeling Paradigms and Analysis of Disease Transmission Models

Author: Abba B. Gumel,Suzanne Lenhart

Publisher: American Mathematical Soc.

ISBN: 0821843842

Category: Mathematics

Page: 268

View: 6677

This volume stems from two DIMACS activities, the U.S.-Africa Advanced Study Institute and the DIMACS Workshop, both on Mathematical Modeling of Infectious Diseases in Africa, held in South Africa in the summer of 2007. It contains both tutorial papers and research papers. Students and researchers should find the papers on modeling and analyzing certain diseases currently affecting Africa very informative. In particular, they can learn basic principles of disease modeling and stability from the tutorial papers where continuous and discrete time models, optimal control, and stochastic features are introduced.

Veterinary Epidemiology

Author: Michael Thrusfield

Publisher: John Wiley & Sons

ISBN: 1118280288

Category: Medical

Page: 888

View: 6070

A comprehensive introduction to the role of epidemiology in veterinary medicine This fully revised and expanded edition of Veterinary Epidemiology introduces readers to the field of veterinary epidemiology. The new edition also adds new chapters on the design of observational studies, validity in epidemiological studies, systematic reviews, and statistical modelling, to deliver more advanced material. This updated edition begins by offering an historical perspective on the development of veterinary medicine. It then addresses the full scope of epidemiology, with chapters covering causality, disease occurrence, determinants, disease patterns, disease ecology, and much more. Veterinary Epidemiology, Fourth Edition: ● Features updates of all chapters to provide a current resource on the subject of veterinary epidemiology ● Presents new chapters essential to the continued advancement of the field ● Includes examples from companion animal, livestock, and avian medicine, as well as aquatic animal diseases ● Focuses on the principles and concepts of epidemiology, surveillance, and diagnostic-test validation and performance ● Includes access to a companion website providing multiple choice questions Veterinary Epidemiology is an invaluable reference for veterinary general practitioners, government veterinarians, agricultural economists, and members of other disciplines interested in animal disease. It is also essential reading for epidemiology students at both the undergraduate and postgraduate levels.

Der Zombie Survival Guide

Überleben unter Untoten

Author: Max Brooks

Publisher: Goldmann Verlag

ISBN: 364108248X

Category: Fiction

Page: 320

View: 7830

Zombies sind längst unter uns. Ein Grund mehr, vorbereitet zu sein! Der Zombie Survival Guide ist der Schlüssel zur erfolgreichen Abwehr von Untoten, die eine ständige Bedrohung für den Menschen darstellen. Mittels hilfreicher Illustrationen und umfassender Informationen deckt dieser Überlebensführer das ganze Spektrum möglicher Angriffs- und Abwehrtechniken ab. Er gibt Ratschläge zu zombiesicherem Wohnen, erläutert Physiologie und typische Verhaltensmuster von Zombies und beschreibt die wichtigsten Utensilien im Kampf gegen diese hinterhältigen Gegner.

A Historical Introduction to Mathematical Modeling of Infectious Diseases

Seminal Papers in Epidemiology

Author: Ivo M. Foppa

Publisher: Academic Press

ISBN: 0128024992

Category: Mathematics

Page: 214

View: 4499

A Historical Introduction to Mathematical Modeling of Infectious Diseases: Seminal Papers in Epidemiology offers step-by-step help on how to navigate the important historical papers on the subject, beginning in the 18th century. The book carefully, and critically, guides the reader through seminal writings that helped revolutionize the field. With pointed questions, prompts, and analysis, this book helps the non-mathematician develop their own perspective, relying purely on a basic knowledge of algebra, calculus, and statistics. By learning from the important moments in the field, from its conception to the 21st century, it enables readers to mature into competent practitioners of epidemiologic modeling. Presents a refreshing and in-depth look at key historical works of mathematical epidemiology Provides all the basic knowledge of mathematics readers need in order to understand the fundamentals of mathematical modeling of infectious diseases Includes questions, prompts, and answers to help apply historical solutions to modern day problems


Author: David B.,Kai Wilksen

Publisher: N.A

ISBN: 9783037310229


Page: 207

View: 418

Modeling and Dynamics of Infectious Diseases

Author: Zhien Ma

Publisher: World Scientific

ISBN: 9814261262

Category: Medical

Page: 355

View: 8530

This book provides a systematic introduction to the fundamental methods and techniques and the frontiers of OCo along with many new ideas and results on OCo infectious disease modeling, parameter estimation and transmission dynamics. It provides complementary approaches, from deterministic to statistical to network modeling; and it seeks viewpoints of the same issues from different angles, from mathematical modeling to statistical analysis to computer simulations and finally to concrete applications.

Entwicklung der Gentherapie

Stellungnahme für Grundsatzfragen der Genforschung, Mitteilung 5

Author: Senatskommission für Grundsatzfragen der Genforschung

Publisher: John Wiley & Sons

ISBN: 3527610537

Category: Science

Page: 88

View: 7474

Seit die DFG im Jahre 1995 eine erste Stellungnahme zum Thema Gentherapie veröffentlichte, hat sich dieses Forschungsfeld ernorm weiterentwickelt. Diese neue Stellungnahme zeigt nun die aktuellen Themen und Perspektiven der gentherapeutischen Forschung auf.